{"id":143999,"date":"2020-12-29T19:25:26","date_gmt":"2020-12-29T16:25:26","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/a-single-gene-invented-hemoglobin-several-times\/"},"modified":"2020-12-29T19:25:26","modified_gmt":"2020-12-29T16:25:26","slug":"a-single-gene-invented-hemoglobin-several-times","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/a-single-gene-invented-hemoglobin-several-times\/","title":{"rendered":"#A single gene ‘invented’ hemoglobin several times"},"content":{"rendered":"

“#A single gene ‘invented’ hemoglobin several times<\/strong>”<\/p>\n

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\n The Platynereis dumerilii vascular system in three segments. Credit: Song et al.\/BMC Evolutionary Biology<\/i>
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Thanks to the marine worm Platynereis dumerilii, an animal whose genes have evolved very slowly, scientists from CNRS, Universit\u00e9 de Paris and Sorbonne Universit\u00e9, in association with others at the University of Saint Petersburg and the University of Rio de Janeiro, have shown that while hemoglobin app<\/a>eared independently in several species, it actually descends from a single gene transmitted to all by their last common ancestor. These findings were published on 29 December 2020 in BMC Evolutionary Biology<\/i>.<\/p>\n


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Having red blood is not peculiar to humans or mammals. This color comes from hemoglobin, a complex protein specialized in transporting the oxygen found in the circulatory system of vertebrates, but also in annelids (a worm family whose most famous members are earthworms), molluscs (especially pond snails) and crustaceans (such as daphnia or ‘water fleas’). It was thought that for hemoglobin to have appeared in such diverse species, it must have been ‘invented’ several times during evolution. But recent research has shown that all of these haemoglobins born ‘independently’ actually derive from a single ancestral gene.<\/p>\n

Researchers from the Institut Jacques Monod (CNRS\/Universit\u00e9 de Paris), the Laboratoire Mati\u00e8re et Syst\u00e8mes Complexes (CNRS\/Universit\u00e9 de Paris), the Station Biologique de Roscoff (CNRS\/Sorbonne Universit\u00e9), the Universities of Saint Petersburg (Russia) and Rio de Janeiro (Brazil), conducted this research on Platynereis dumerilii, a small marine worm with red blood.<\/p>\n

It is considered to be an animal that evolved slowly, because its genetic characteristics are close to those of the marine ancestor of most animals, Urbilateria. Studying these worms by comparing them with other species with red blood has helped in tracing back to the origins of haemoglobins.<\/p>\n

The research focused on the broad family to which haemoglobins belong: globins, proteins present in almost all living beings that ‘store’ gases like oxygen and nitric oxide. But globins usually act inside the cells because they do not circulate in the blood like hemoglobin.<\/p>\n

This work shows that in all species with red blood, it is the same gene that makes a globin called ‘cytoglobin’ that independently evolved to become a hemoglobin-encoding gene. This new circulating molecule made oxygen transport more efficient in their ancestors, who became larger and more active.<\/p>\n

Scientists now want to change scale and continue this work by studying when and how the different specialized cells of bilaterian vascular systems emerged.<\/p>\n\n

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What happens to magnetic nanoparticles in cells?\n <\/p><\/div>\n

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\n More information:<\/strong>
\n Sol\u00e8ne Song et al, Globins in the marine annelid Platynereis dumerilii shed new light on hemoglobin evolution in bilaterians, BMC Evolutionary Biology<\/i> (2020). DOI: 10.1186\/s12862-020-01714-4<\/a><\/p><\/div>\n
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\n Song et al. \/ BMC Evolutionary Biology
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Citation<\/strong>:
\n A single gene ‘invented’ hemoglobin several times (2020, December 29)
\n retrieved 30 December 2020
\n from https:\/\/phys.org\/news<\/a>\/2020-12-gene-hemoglobin.html<\/p>\n

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\n part may be reproduced without the written permission. The content is provided for information purposes only.<\/p><\/div>\n<\/p><\/div>\n