{"id":149774,"date":"2021-01-07T23:22:45","date_gmt":"2021-01-07T20:22:45","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/identical-twins-arent-perfect-clones-research-shows\/"},"modified":"2021-01-07T23:22:45","modified_gmt":"2021-01-07T20:22:45","slug":"identical-twins-arent-perfect-clones-research-shows","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/identical-twins-arent-perfect-clones-research-shows\/","title":{"rendered":"#Identical twins aren\u2019t perfect clones, research shows"},"content":{"rendered":"

“#Identical twins aren\u2019t perfect clones, research shows<\/strong>”
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WASHINGTON \u2014 If you\u2019re an identical twin who\u2019s always resisted being called a clone of your sibling, scientists say you have a point.<\/p>\n

Identical twins are not exactly genetically the same, new research shows.<\/p>\n

Scientists in Iceland sequenced DNA from 387 pairs of identical twins \u2014 those derived from a single fertilized egg \u2014 as well as from their parents, children and spouses. That allowed them to find \u201cearly mutations that separate identical twins,\u201d said Kari Stefansson, a geneticist at the University of Iceland and the company deCODE genetics and co-author of the\u00a0paper\u00a0<\/a>published Thursday in the journal Nature Genetics.<\/p>\n

A mutation means an alteration in a sequence of DNA \u2014 a tiny change that is not inherently good or bad, but can influence physical features or susceptibility to certain diseases. They can occur when a cell divides and makes a slight error in replicating DNA.<\/p>\n

On average, identical twins have 5.2 of these early genetic differences, the researchers found. But about 15 percent of identical twin pairs have more genetic differences, some of them up to 100, said Stefansson.<\/p>\n

These differences represent a tiny portion of each twin\u2019s genetic code, but they could influence why one twin is taller or why one twin is at greater risk for certain cancers.<\/p>\n

Previously, many researchers believed that physical differences between identical twins were related mostly to environmental factors, such as nutrition or lifestyle.<\/p>\n

Jan Dumanski, a geneticist at Uppsala University in Sweden, who was not involved in the new paper, praised it as \u201ca clear and important contribution\u201d to medical research.<\/p>\n

\u201cThe implication is that we have to be very careful when we are using twins as a model\u201d for teasing apart the influences of nature and nurture, he said.<\/p>\n

Previous studies, including a 2008\u00a0paper\u00a0<\/a>in The American Journal of Human Genetics, have identified some genetic differences between identical twins.<\/p>\n

The new study goes beyond earlier work by including DNA of parents, children and spouses of identical twins. That allowed the researchers to pinpoint when genetic mutations occurred in two different kinds of cells \u2014 those present in just one individual and those inherited by that person\u2019s children. They also found mutations that occurred before the developing embryo split into two, setting the stage for twins.<\/p>\n

Stefansson said that his team had found pairs of twins where a mutation is present in all cells of the body of one twin, but not found in the other twin at all. However, \u201csometimes the second twin may show the mutation in some cells, but not all cells,\u201d he said.<\/p>\n

Nancy Segal, a psychologist who studies twins at California State University, Fullerton and was not involved in the paper, called the research \u201cheroic and really significant.\u201d<\/p>\n

\u201cThis will force scientists to refine our thinking about the influences of genetics and environment,\u201d she said. \u201cTwins are very alike, but it is not a perfect similarity.\u201d<\/p><\/div>\n

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Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

“#Identical twins aren\u2019t perfect clones, research shows” WASHINGTON \u2014 If you\u2019re an identical twin who\u2019s always resisted being called a clone of your sibling, scientists say you have a point. Identical twins are not exactly genetically the same, new research shows. Scientists in Iceland sequenced DNA from 387 pairs of identical twins \u2014 those derived…<\/p>\n","protected":false},"author":1,"featured_media":149775,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2021\/01\/Not-Identical-Twins.jpg?quality=90&strip=all&w=1200","fifu_image_alt":"","footnotes":""},"categories":[70897],"tags":[88727,70508,61514,67907,37692],"class_list":["post-149774","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-1-7-21","tag-dna","tag-research","tag-science","tag-twins"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/149774","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=149774"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/149774\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/149775"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=149774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=149774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=149774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}