{"id":186400,"date":"2021-02-23T00:58:50","date_gmt":"2021-02-22T21:58:50","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/research-team-identifies-potential-drug-to-treat-sars-cov-2\/"},"modified":"2021-02-23T00:58:50","modified_gmt":"2021-02-22T21:58:50","slug":"research-team-identifies-potential-drug-to-treat-sars-cov-2","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/research-team-identifies-potential-drug-to-treat-sars-cov-2\/","title":{"rendered":"#Research team identifies potential drug to treat SARS-CoV-2"},"content":{"rendered":"

“#Research team identifies potential drug to treat SARS-CoV-2<\/strong>”<\/p>\n

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\"SARS-CoV-2
\n Novel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: National Institute of Allergy and Infectious Diseases, NIH
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A federally app<\/a>roved heart medication shows significant effectiveness in interfering with SARS-CoV-2 entry into the human cell host, according to a new study by a research team from Texas A&M University and The University of Texas Medical Branch (UTMB).<\/p>\n

The medication bepridil, which goes by the trade name Vascor, is currently approved by the U.S. Food and Drug Administration (FDA) to treat angina, a heart condition.<\/p>\n

The team’s leaders are College of Science<\/a> professor Wenshe Ray Liu, professor and holder of the Gradipore Chair in the Department of Chemistry at Texas A&M, and Chien-Te Kent Tseng, professor and director of the SARS\/MERS\/COVID-19 Laboratory at UTMB. Liu also holds joint faculty positions in Texas A&M’s colleges of medicine and agriculture and life sciences.<\/p>\n

“Only one medication is currently available, Remdesivir, to provide limited benefits to COVID-19 patients, and the virus may easily evade it,” Liu said. “Finding alternative medicines is imperative. Our team screened more than 30 FDA\/European Medicines Agency approved drugs for their ability to inhibit SARS-COV-2’s entry into human cells. The study found bepridil to offer the most potential for treatment of COVID-19. As a result, we are advocating for the serious consideration of using bepridil in clinical tests related to SARS-CoV-2.”<\/p>\n

The Texas A&M-UTMB study is now available at the website of the peer-reviewed Proceedings of the National Academy of Sciences<\/i> (PNAS<\/i>) and is scheduled for print publication on March 9.<\/p>\n

The team, which includes six other researchers from Texas A&M and four from UTMB, now plans to advance their work to animal models with a potential for clinical trials.\n <\/p>\n\n

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Follow the latest news<\/a> on the coronavirus (COVID-19) outbreak\n <\/p><\/div>\n

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\n More information:<\/strong>
\n Erol C. Vatansever et al, Bepridil is potent against SARS-CoV-2 in vitro, Proceedings of the National Academy of Sciences<\/i> (2021). DOI: 10.1073\/pnas.2012201118<\/a><\/p><\/div>\n
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\n Texas A&M University
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Citation<\/strong>:
\n Research team identifies potential drug to treat SARS-CoV-2 (2021, February 22)
\n retrieved 22 February 2021
\n from https:\/\/medicalxpress.com\/news\/2021-02-team-potential-drug-sars-cov-.html<\/p>\n

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