{"id":203339,"date":"2021-03-15T22:37:17","date_gmt":"2021-03-15T19:37:17","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/researchers-identify-50-additional-genes-for-eye-color\/"},"modified":"2021-03-15T22:37:17","modified_gmt":"2021-03-15T19:37:17","slug":"researchers-identify-50-additional-genes-for-eye-color","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/researchers-identify-50-additional-genes-for-eye-color\/","title":{"rendered":"#Researchers identify 50 additional genes for eye color"},"content":{"rendered":"

“#Researchers identify 50 additional genes for eye color<\/strong>”
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An international team of\u00a0scientists\u00a0has identified 50 more\u00a0genes\u00a0for\u00a0eye\u00a0color.<\/p>\n

In a 12-page study published Thursday in the\u00a0peer-reviewed journal Science<\/a> Advances, researchers led by\u00a0King\u2019s College\u00a0London\u00a0and\u00a0Erasmus University Medical Center Rotterdam\u00a0examined the genetic analysis of almost\u00a0195,000 people from 10 populations across both\u00a0Europe\u00a0and\u00a0Asia.<\/p>\n

\u201cWe knew of all these people whether they had brown, blue or any other color eyes.\u00a0Computers\u00a0searched their DNA for areas that have something to do with eye color.\u00a0In this way, we found 61 genes associated with eye color, 50 of which were still unknown,\u201d Dr. Manfred Kayser of the Erasmus University Medical Center Rotterdam, said in\u00a0an article<\/a>\u00a0on the university\u2019s website.<\/p>\n

\u201cMany genes had to do with pigmentation, but we also found genes that say something about the structure and formation of the iris,\u201d the study\u2019s senior co-author added.<\/p>\n

In\u00a0the report\u2019s abstract<\/a>, the researchers said they had identified\u00a0124 independent associations<\/a>.\u00a0<\/p>\n

A genetic association study tests whether a given sequence \u2014 like a gene \u2014 has involvement in controlling the phenotype of a specific trait, metabolic pathway, or disease by comparing\u00a0genetic material,\u00a0according to Nature<\/a>.\u00a0<\/p>\n

\u201cWe find evidence for genes involved in melanin pigmentation, but we also find associations with genes involved in iris morphology and structure,\u201d the abstract\u00a0said. \u201cFurther analyses in 1,636 Asian participants from two populations suggest that iris pigmentation variation in Asians is genetically similar to Europeans, albeit with smaller effect sizes.\u201d<\/p>\n

In\u00a0layman\u2019s terms, the researchers found that eye color in people who are Asian\u00a0with different shades of brown is genetically similar to the eye color in Europeans ranging from dark brown to light blue.<\/p>\n

The group said their findings collectively explain\u00a053.2% of eye color variation using \u201ccommon single-nucleotide polymorphisms\u201d or SNPs.<\/p>\n

SNPs<\/a>\u00a0are\u00a0a variation at a single position in a DNA sequence among individuals.\u00a0<\/p>\n

\u201cOverall, our study outcomes demonstrate that the genetic complexity of human eye color considerably exceeds previous knowledge and expectations, highlighting eye color as a genetically highly complex human trait,\u201d the abstract concludes.<\/p>\n

In an\u00a0accompanying release<\/a>, King\u2019s College London said the results would help to improve ophthalmologists\u2019 understanding of eye diseases like\u00a0pigmentary glaucoma and ocular albinism.<\/p>\n

They also noted that the study \u2014 the largest\u00a0genetic study of its kind to date \u2014 was built on previous research\u00a0in which scientists had identified a dozen genes linked to eye color and that it had initially been believed that variation in eye color was controlled by only a couple genes with brown eyes\u00a0dominant over blue eyes.<\/p>\n

\u201cThe findings are exciting because they bring us to a step closer to understanding the genes that cause one of the most striking features of the human faces, which has mystified generations throughout our history,\u201d Kings College London\u2019s Dr. Pirro Hysi, also a co-senior author, said in the release. \u201cThis will improve our understanding of many diseases that we know are associated with specific pigmentation levels.\u201d<\/p>\n

\u201cThis study delivers the genetic knowledge needed to improve eye color prediction from DNA as already app<\/a>lied in anthropological and forensic studies, but with limited accuracy for the non-brown and non-blue eye colors,\u201d Kayser told Kings College London.\n <\/p><\/div>\n

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Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

“#Researchers identify 50 additional genes for eye color” An international team of\u00a0scientists\u00a0has identified 50 more\u00a0genes\u00a0for\u00a0eye\u00a0color. In a 12-page study published Thursday in the\u00a0peer-reviewed journal Science Advances, researchers led by\u00a0King\u2019s College\u00a0London\u00a0and\u00a0Erasmus University Medical Center Rotterdam\u00a0examined the genetic analysis of almost\u00a0195,000 people from 10 populations across both\u00a0Europe\u00a0and\u00a0Asia. \u201cWe knew of all these people whether they had brown,…<\/p>\n","protected":false},"author":1,"featured_media":203340,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2021\/03\/eye-feature.jpg?quality=90&strip=all&w=1200","fifu_image_alt":"","footnotes":""},"categories":[70897],"tags":[97778,94060,70510,5050,9724],"class_list":["post-203339","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-3-15-21","tag-eyes","tag-genetics","tag-scientists","tag-study-says"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/203339","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=203339"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/203339\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/203340"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=203339"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=203339"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=203339"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}