{"id":204511,"date":"2021-03-17T19:14:17","date_gmt":"2021-03-17T16:14:17","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/meds-for-enlarged-prostate-tied-to-heart-failure-risk\/"},"modified":"2021-03-17T19:14:17","modified_gmt":"2021-03-17T16:14:17","slug":"meds-for-enlarged-prostate-tied-to-heart-failure-risk","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/meds-for-enlarged-prostate-tied-to-heart-failure-risk\/","title":{"rendered":"#Meds for enlarged prostate tied to heart failure risk"},"content":{"rendered":"

“#Meds for enlarged prostate tied to heart failure risk<\/strong>”<\/p>\n

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(HealthDay)\u2014Medications used for enlarged prostate are associated with a small, but significant, increase in developing heart failure, according to a study published online Feb. 22 in The<\/i> Journal of Urology<\/i>.<\/p>\n

Avril Lusty, M.D., from Queen’s University in Kingston, Ontario, Canada, and colleagues used administrative databases to identify 175,201 men older than 66 years with a diagnosis of benign prostatic hyperplasia (BPH) between 2005 and 2015. The primary outcome of new cardiac failure was compared for men with 5-alpha reductase inhibitor (5ARI) exposure and\/or alpha-blocker (\u03b1-blocker) exposure.<\/p>\n

The researchers identified 8,339 men exposed to 5ARI, 55,383 exposed to \u03b1-blockers, and 41,491 using combination therapy. There was a higher risk observed for cardiac failure among men treated with 5ARI and \u03b1-blocker, alone or in combination, versus men with no medication use. The risk for cardiac failure was highest for \u03b1-blockers alone (hazard ratio [HR], 1.22; 95 percent confidence interval [CI], 1.18 to 1.26), intermedia<\/a>te for combination \u03b1-blockers\/5ARIs (HR, 1.16; 95 percent CI, 1.12 to 1.21), and lowest for 5ARI alone (HR, 1.09; 95 percent CI, 1.02 to 1.17). The risk for cardiac failure was higher for nonselective \u03b1-blockers than selective \u03b1-blockers (HR, 1.08; 95 percent CI, 1.00 to 1.17).<\/p>\n

“This is an important finding, given that BPH is so common among older men, and that these medications are so widely used,” a coauthor said in a statement.\n <\/p>\n\n

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Medications for enlarged prostate linked to heart failure risk\n <\/p><\/div>\n

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\n retrieved 17 March 2021
\n from https:\/\/medicalxpress.com\/news<\/a>\/2021-03-meds-enlarged-prostate-tied-heart.html<\/p>\n

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