{"id":221410,"date":"2021-04-07T22:59:50","date_gmt":"2021-04-07T19:59:50","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/carnegie-mellon-yale-pna-based-technique-an-essential-part-of-the-gene-editing-toolkit\/"},"modified":"2021-04-07T22:59:50","modified_gmt":"2021-04-07T19:59:50","slug":"carnegie-mellon-yale-pna-based-technique-an-essential-part-of-the-gene-editing-toolkit","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/carnegie-mellon-yale-pna-based-technique-an-essential-part-of-the-gene-editing-toolkit\/","title":{"rendered":"#Carnegie Mellon\/Yale PNA-based technique an essential part of the gene editing toolkit"},"content":{"rendered":"

“#Carnegie Mellon\/Yale PNA-based technique an essential part of the gene editing toolkit<\/strong>”<\/p>\n

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In an article published in the April 8 issue of Nature<\/i>, the National Institutes of Health’s Somatic Cell Gene Editing Consortium provided a detailed update on the progress of their nationwide effort to develop safer and more effective methods to edit the genomes of disease-relevant somatic cells and reduce the burden of disease caused by genetic changes.<\/p>\n


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Gene editing allows scientists to modify sections of an organism’s DNA and is considered a promising treatment for a number of genetic diseases. There have been numerous advances in the laboratory over the last few decades, but there are still many challenges to overcome before gene editing can be widely used in the patient population. Launched in 2018, the Somatic Cell Gene Editing Consortium<\/a> (SCGE) has brought together some of the leading researchers in the field to advance discovery and accelerate the translation of somatic gene editing advances in the lab to the clinical setting.<\/p>\n

Over six years, the NIH will allocate app<\/a>roximately $190 million to SCGE to realize gene editing’s potential. The end result will be a freely available toolkit that will provide the biomedical research community with rigorously evaluated information about genome editors and methods for delivering and tracking gene editing molecules.<\/p>\n

“NIH realized it was important for all of us who are investigating gene editing to work together toward a common goal,” said Carnegie Mellon University Professor of Chemistry Danith Ly who joined the consortium in 2019. “We’re designing molecules that can go into the cell and we’re cataloging each and every one. What we’ll end up with is a very valuable, rigorously evaluated resource for those who want to bring gene editing to patients.”<\/p>\n


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