{"id":227087,"date":"2021-04-15T01:20:37","date_gmt":"2021-04-14T22:20:37","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/"},"modified":"2021-04-15T01:20:37","modified_gmt":"2021-04-14T22:20:37","slug":"the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/","title":{"rendered":"#The P.1 variant from Brazil is spreading in Canada. What do we know about it?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a2d25ffd3220\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a2d25ffd3220\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/#Why_is_P1_considered_a_variant_of_concern\" >Why is P.1 considered a variant of concern?\u00a0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/#Who_is_at_highest_risk_from_P1_Does_it_like_B117_have_more_of_an_adverse_impact_on_younger_healthier_people_than_classic_COVID\" >Who is at highest risk from P.1? Does it, like B.1.1.7, have more of an adverse impact on younger, healthier people than classic COVID?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/#Does_P1_take_over_the_way_B117_does\" >Does P.1 take over the way B.1.1.7 does?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/#Why_are_there_so_many_P1_cases_in_BC\" >Why are there so many P.1 cases in B.C.?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/buradabiliyorum.com\/en\/the-p-1-variant-from-brazil-is-spreading-in-canada-what-do-we-know-about-it\/#Are_the_vaccines_effective_against_P1\" >Are the vaccines effective against P.1?<\/a><\/li><\/ul><\/nav><\/div>\n<p>&#8220;<strong>#The P.1 variant from Brazil is spreading in Canada. What do we know about it?<\/strong>&#8221;<\/p>\n<div>\n                                                                        <span style=\"font-weight: 400;\">\u201cI learned about P.1 in late December 2020, and it made my head spin,\u201d says <\/span><span style=\"font-weight: 400;\">Dr. Sarah Otto, Canada Research Chair in theoretical and experimental evolution<\/span><span style=\"font-weight: 400;\">. \u201cA year had passed without a major evolutionary shift in SARS-CoV-2. Then, over the course of a month, two major variants of concern were announced [B.1.1.7 from the U.K. and P.1 from Brazil], with a third soon following [B.1.351 from South Africa].\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Those three variants of concern (VOCs) are all now in Canada. B.1.1.7 dominates, accounting for 43,600 confirmed cases, while there are 1,813 P.1. cases and 378 cases of B.1.351. The vast majority of the P.1 cases are in British Columbia: 1,529, according to <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.ctvnews.ca\/health\/coronavirus\/tracking-variants-of-the-novel-coronavirus-in-canada-1.5296141\"><span style=\"font-weight: 400;\">CTV\u2019s variant tracker,<\/span><\/a><span style=\"font-weight: 400;\"> followed by Ontario with 178 cases, Alberta with 102 cases and six in Quebec.\u00a0<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_is_P1_considered_a_variant_of_concern\"><\/span><b>Why is P.1 considered a variant of concern?\u00a0<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cEvery virus is going to pick up some genetic variation and much of it won\u2019t really matter,\u201d explains Dr. Caroline Colijn, Canada 150 Research Chair in mathematics for evolution, infection and public health. \u201cBut the reason we call these variants of concern is that we <\/span><i><span style=\"font-weight: 400;\">are <\/span><\/i><span style=\"font-weight: 400;\">concerned about them.\u201d In particular, she explains, scientists look for three factors: whether the variant is more infectious; whether illness resulting from variant infection is more severe; and whether the variant<\/span> <span style=\"font-weight: 400;\">can undermine a person\u2019s immunity even if that person had already had COVID.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both Colijn and Otto say P.1 <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ears to hit the trifecta. \u201c<\/span><span style=\"font-weight: 400;\">Evidence from Brazil suggests it is a <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/trip-and-travel\/\" data-internallinksmanager029f6b8e52c=\"10\" title=\"Trip &amp; Travel\" target=\"_blank\" rel=\"noopener\">trip<\/a>le whammy\u2014it spreads faster (40-120 per cent), can overcome immunity of previously infected individuals (25-61 per cent more frequently than \u201cclassic COVID\u201d), and is more lethal (by 10-80 per cent),\u201d detailed Otto, who is also <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.zoology.ubc.ca\/~otto\/\"><span style=\"font-weight: 400;\">a zoology professor at the University of British Columbia<\/span><\/a><span style=\"font-weight: 400;\">, in an email to <\/span><i><span style=\"font-weight: 400;\">Maclean\u2019s<\/span><\/i><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Who_is_at_highest_risk_from_P1_Does_it_like_B117_have_more_of_an_adverse_impact_on_younger_healthier_people_than_classic_COVID\"><\/span><b>Who is at highest risk from P.1? Does it, like B.1.1.7, have more of an adverse impact on younger, healthier people than classic COVID?<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cInitial data suggests that P.1 impacts everybody more severely. This, along with the fact that we have vaccinated the most vulnerable elderly population in many places, mean that younger adults now represent a much larger fraction of those in hospital and critical care,\u201d <\/span>says Otto.<\/p>\n<p><span style=\"font-weight: 400;\">One of the mutations in P.1. is called E484K, which it shares with the B.1.351 variant (but is not currently found in B.1.1.7, though that mutation could occur, Colijn says).<\/span> <span style=\"font-weight: 400;\">It is located in the spike protein and is called an \u201cescape mutation\u201d because it helps the virus slip past immune defences built as a result of previous exposure, according to <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.bmj.com\/content\/372\/bmj.n359\"><span style=\"font-weight: 400;\">an analysis in the <\/span><i><span style=\"font-weight: 400;\">British Medical Journal<\/span><\/i><\/a><span style=\"font-weight: 400;\">. In other words,<\/span> <span style=\"font-weight: 400;\">P.1 has the ability to overcome the immunity developed by people previously infected with COVID-19.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another attribute that all three VOCs share is \u201cone additional mutation that deletes a small part of the drably named \u2018non-structural protein 6\u2019 (NSP6),\u201d Otto explained earlier this year in <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/theconversation.com\/why-new-covid-19-variants-are-on-the-rise-and-spreading-around-the-world-153530\"><i><span style=\"font-weight: 400;\">The Conversation<\/span><\/i><\/a><span style=\"font-weight: 400;\">. \u201cWe don\u2019t yet know what the deletion does, but\u2026[it] might alter the ability of the virus to take hold and replicate within our cells.\u201d In other words, it\u2019s more likely to take hold.\u00a0<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Does_P1_take_over_the_way_B117_does\"><\/span><b>Does P.1 take over the way B.1.1.7 does?<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">How P.1. will fare against the dominant VOC of B.1.1.7 isn\u2019t certain. A <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2021.04.06.21254923v1\"><span style=\"font-weight: 400;\">preprint study published on MedRxiv on April 7 looked at that interaction<\/span><\/a><span style=\"font-weight: 400;\"> in Italy by measuring the proportion of P.1 cases in central Italy over a month. It found no change in that overall percentage, \u201c<\/span><span style=\"font-weight: 400;\">suggesting the inability by this lineage to outcompete B.1.1.7.\u201d\u00a0<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_are_there_so_many_P1_cases_in_BC\"><\/span><b>Why are there so many P.1 cases in B.C.?<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">P.1 was first detected <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nytimes.com\/interactive\/2021\/health\/coronavirus-variant-tracker.html\"><span style=\"font-weight: 400;\">after a group of travellers returned to Japan from a trip to Brazil<\/span><\/a><span style=\"font-weight: 400;\">. Researchers then traced the P.1 VOC to the Amazonian city of Manaus, where it emerged in December 2020. Its highly infectious nature meant it quickly became the dominant strain in Brazil. It\u2019s in Manaus where researchers discovered that people previously infected during the city\u2019s big first wave were being reinfected.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">On Feb. 8, Ontario confirmed the first case of P.1 in Canada through genomic testing. That case was linked to international travel from<\/span> <span style=\"font-weight: 400;\">Brazil, according <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/nccid.ca\/covid-19-variants\/\"><span style=\"font-weight: 400;\">to the National Collaborating Centre for Infectious Diseases<\/span><\/a><span style=\"font-weight: 400;\">. On March 9, <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/globalnews.ca\/news\/7686805\/bc-coronavirus-update-march-9-2021-2\/\"><span style=\"font-weight: 400;\">British Columbia reported its first case of<\/span><\/a><span style=\"font-weight: 400;\"> P.1. The next day, the <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/vancouversun.com\/news\/local-news\/covid-19-new-b-c-care-home-outbreaks-a-warning-about-limits-of-vaccination\"><span style=\"font-weight: 400;\">province reported another 13 cases<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In particular, it is widely prevalent in the ski resort of Whistler, which closed after more than 1,500 cases were reported since the new year. While there\u2019s a low risk of contracting the virus while actually skiing, such resorts, with their congregate housing<\/span> <span style=\"font-weight: 400;\">and indoor gatherings, have proved to be good places for spreading the virus, Colijn notes. Now, British Columbia is vaccinating everyone who lives or works in Whistler in an effort to stop the outbreak. The P.1 variant is believed responsible for many cases in the\u00a0<a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/theprovince.com\/sports\/hockey\/nhl\/vancouver-canucks\/a-bc-cdc-change-in-testing-was-a-big-clue-in-determining-canucks-p-1-variant\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/theprovince.com\/sports\/hockey\/nhl\/vancouver-canucks\/a-bc-cdc-change-in-testing-was-a-big-clue-in-determining-canucks-p-1-variant&amp;source=gmail&amp;ust=1618517773115000&amp;usg=AFQjCNHOGMWTXWyZt7Cy2TriuMOVSlTDIw\">outbreak among players and staff in the Vancouver Canucks organization<\/a>\u00a0that caused the NHL team to suspend its\u00a0<a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nhl.com\/canucks\/schedule\/2021-03-01\/PT\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.nhl.com\/canucks\/schedule\/2021-03-01\/PT&amp;source=gmail&amp;ust=1618517773115000&amp;usg=AFQjCNG056_DKzrEyg9TFscGMfsgC6i5Rw\">games after the team lost 5-1 to Winnipeg on March 24<\/a>.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">All three VOCs arrived and spread in Canada through travellers. Although experts warned about that risk, the border restrictions imposed by federal and provincial governments were full of holes, says Colijn, who is also a mathematics professor at Simon Fraser University. For example, t<\/span><span style=\"font-weight: 400;\">hough passengers arriving in Canada on international flights need PCR tests as well as hotel stays and quarantines, others \u201care taking taxis across the U.S. border,\u201d she notes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cI feel we\u2019ve lost an opportunity, and I\u2019m still mourning that loss,\u201d<\/span> <span style=\"font-weight: 400;\">she says. \u201cWe thought it was self-evident that [we wouldn\u2019t want] something that was 40-to-100 per cent more transmissible, and maybe more severe in Canada, and maybe we would take steps to stop that from happening.\u201d\u00a0<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Are_the_vaccines_effective_against_P1\"><\/span><b>Are the vaccines effective against P.1?<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Scientists are seeing signs<\/span> <span style=\"font-weight: 400;\">that vaccines are less effective against B.1.351<\/span> <span style=\"font-weight: 400;\">and their concern is that the same may hold true for P.1, given that the variants share the E484K mutation. Currently, there isn\u2019t solid data as to how existing vaccines hold up against P.1.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When asked if P.1 could mutate into something even worse, Otto explains, \u201cThe worst-case scenario is that we have so many cases of COVID-19 that variants build up mutations that evade our immune response, rendering our current [efforts]<\/span> <span style=\"font-weight: 400;\">ineffective over the course of the year.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cBut I\u2019m actually mainly hopeful,\u201d she continues. \u201cThe U.K. and Israel have vaccinated a large portion of the population and haven\u2019t seen a resurgence of COVID-19; [there are]<\/span> <span style=\"font-weight: 400;\">no signs of a major escape mutation. I\u2019m also hopeful because our immune systems are incredible\u2014they throw an arsenal of responses from antibodies to T cells and B cells. So it\u2019s actually hard for a virus to escape our immune system, because it isn\u2019t just one thing that it has to escape from.\u00a0 And even if it can escape the arsenal in me, that doesn\u2019t mean it can escape the arsenal in you, because everybody develops a different immune reaction.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As for Colijn, one of the things she\u2019s losing sleep over is the fact that Canada is <\/span><span style=\"font-weight: 400;\">relying on vaccinations as the cornerstone for our way out of this crisis, the idea being that once we vaccinate everyone, the pandemic is going to end. She worries about a new VOC being discovered in a large country where vaccination is widespread. It may be like P.1 but even better at getting into immunized people. And what if that VOC was found in a country like the U.S. or Britain, with which Canada has lots of international travel? she asks.\u00a0\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Then, Colijn asks, \u201cAre we going to actually decide as a country that we don\u2019t want that [variant of concern]<\/span> <span style=\"font-weight: 400;\">to establish itself [here]? Or are we going to take the same attitude of closing half the holes and say, \u2018Oh no, that will be fine, nothing to worry about, no special measures are needed, there is no data to say this is a problem in Canada.\u2019 Are we going to do this <\/span><i><span style=\"font-weight: 400;\">again<\/span><\/i><span style=\"font-weight: 400;\">?\u201d<\/span><i><span style=\"font-weight: 400;\">\u00a0<\/span><\/i><br \/>\n<span class=\"ctx-article-root\"><!-- --><\/span><\/p><\/div>\n<p><script async defer crossorigin=\"anonymous\" src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js#xfbml=1&#038;version=v10.0\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">News<\/a> articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/general\/\" target=\"_blank\" rel=\"noopener\">General category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.macleans.ca\/news\/the-p-1-variant-is-spreading-in-canada-what-do-we-know-about-it\/\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;#The P.1 variant from Brazil is spreading in Canada. What do we know about it?&#8221; \u201cI learned about P.1 in late December 2020, and it made my head spin,\u201d says Dr. Sarah Otto, Canada Research Chair in theoretical and experimental evolution. \u201cA year had passed without a major evolutionary shift in SARS-CoV-2. Then, over the&#8230;<\/p>\n","protected":false},"author":1,"featured_media":227088,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/www.macleans.ca\/wp-content\/uploads\/2021\/04\/SignAboutVariants-766x431.jpeg","fifu_image_alt":"","footnotes":""},"categories":[1],"tags":[82947,67806,102099,102100],"class_list":["post-227087","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","tag-covid-vaccines","tag-editors-picks","tag-p-1-variant","tag-variants-of-concern"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/227087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=227087"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/227087\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/227088"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=227087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=227087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=227087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}