{"id":300677,"date":"2021-07-16T11:05:12","date_gmt":"2021-07-16T08:05:12","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/aussie-scientists-see-life-saving-potential-in-spider-venom\/"},"modified":"2021-07-16T11:05:12","modified_gmt":"2021-07-16T08:05:12","slug":"aussie-scientists-see-life-saving-potential-in-spider-venom","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/aussie-scientists-see-life-saving-potential-in-spider-venom\/","title":{"rendered":"#Aussie scientists see life-saving potential in spider venom"},"content":{"rendered":"

“#Aussie scientists see life-saving potential in spider venom<\/strong>”<\/p>\n

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\"Funnel-web
\n Funnel-web spiders are among the world’s deadliest species.
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A group of Australia-based scientists are looking to venom from a deadly native spider to actually save lives, by halting the harmful effects of heart attacks.\n <\/p>\n

Researchers used venom from a type of funnel-web spider\u2014among the world’s deadliest species\u2014in a drug they hope can soon be taken to human trials.<\/p>\n

So far the experimental medicine has only been lab-tested.<\/p>\n

University of Queensland scientist Nathan Palpant said Friday the venom helped stop the body sending a “death signal” after a heart attack, which causes cells to die.<\/p>\n

“After a heart attack, blood flow to the heart is reduced, resulting in a lack of oxygen to heart muscle,” Palpant said.<\/p>\n

“The lack of oxygen causes the cell environment to become acidic, which combine to send a message for heart cells to die. <\/p>\n

“Despite decades of research, no one has been able to develop a drug that stops this death signal in heart cells, which is one of the reasons why heart disease continues to be the leading cause of death in the world.”<\/p>\n

The team has successfully used a protein from spider venom on beating human heart cells that were exposed to heart-attack stresses.<\/p>\n

“The Hi1a protein from spider venom blocks acid-sensing ion channels in the heart, so the death message is blocked, cell death is reduced, and we see improved heart cell survival,” Palpant said.<\/p>\n

It is hoped the drug could help not only prevent heart damage and save lives, but improve the quality of donated hearts during transplants.<\/p>\n

Previous research has indicated funnel-web spider venom may also be useful in curbing damage from strokes.<\/p>\n

The University of Queensland said the team was aiming for human clinical trials for both stroke and heart disease “within two to three years”.<\/p>\n

The most recent research was published in the latest edition of the journal Circulation<\/i>.\n <\/p>\n\n

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Revealing the mysteries of stonefish venom<\/a>\n <\/div>\n

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\n More information:<\/strong>
\n Meredith A. Redd et al, Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury, Circulation<\/i> (2021). DOI: 10.1161\/circulationaha.121.054360<\/a><\/p><\/div>\n

\n \u00a9 2021 AFP<\/p>\n

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Citation<\/strong>:
\n Aussie scientists see life-saving potential in spider venom (2021, July 16)
\n retrieved 16 July 2021
\n from https:\/\/medicalxpress.com\/news<\/a>\/2021-07-aussie-scientists-life-saving-potential-spider.html<\/p>\n

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