{"id":312814,"date":"2021-07-30T19:40:02","date_gmt":"2021-07-30T16:40:02","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/race-free-equations-for-glomerular-filtration-rate-compared\/"},"modified":"2021-07-30T19:40:02","modified_gmt":"2021-07-30T16:40:02","slug":"race-free-equations-for-glomerular-filtration-rate-compared","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/race-free-equations-for-glomerular-filtration-rate-compared\/","title":{"rendered":"#Race-free equations for glomerular filtration rate compared"},"content":{"rendered":"

“#Race-free equations for glomerular filtration rate compared<\/strong>”<\/p>\n

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\"Race-free<\/figure>\n<\/div>\n<\/div>\n

(HealthDay)\u2014The chronic kidney disease (CKD) Epidemiology Consortium estimated glomerular filtration rate cystatin C (eGFRcys), the only guideline-recommended equation that does not require race, results in the smallest changes to eGFR among Black patients, according to a research letter published online July 29 in the Journal of the American Society of Nephrology<\/i>.<\/p>\n

James A. Diao, from Boston Children’s Hospital, and colleagues compared eGFR distributions for race-free eGFR equations and equations using serum creatinine and requiring race (eGFRcr and eGFRcr-cys [computed from creatinine and cystatin C, respectively]). The distributions of eGFR were compared using data from the National Health and Nutrition Examination Survey, for a sample of 4,434 nonpregnant adults from 1999 to 2002.<\/p>\n

The researchers found that eGFRcys resulted in the smallest change in CKD prevalence among Black adults relative to eGFRcr-cys (0.7 percent) compared to race-blended or race-removed equations (1.4 to 4.5 percent). The smallest media<\/a>n change in eGFR in Black adults was seen with eGFRcys (\u22120.8 mL\/min\/1.73 m2<\/sup>) compared with other race-free alternatives, which varied from 11.3 to 29.0 for race-blended and race-removed models, respectively. The smallest gap in CKD prevalence between Black and White\/other patients was seen with eGFRcys (3.7 percent) relative to other race-free equations (6.1 to 7.4 percent).<\/p>\n

“Our findings indicate that race-free alternatives may vary considerably in effects on chronic kidney disease classification,” a coauthor said in a statement. “We hope these estimates will be useful to the many individuals and groups working to improve kidney function estimation without race.”\n <\/p>\n\n

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The effects of eliminating race-based adjustments in estimates of kidney function\n <\/p><\/div>\n

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\n More information:<\/strong>
\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p><\/div>\n

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\n Race-free equations for glomerular filtration rate compared (2021, July 30)
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