{"id":442754,"date":"2022-05-06T09:40:57","date_gmt":"2022-05-06T06:40:57","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/virus-found-in-pig-heart-used-in-human-transplant\/"},"modified":"2022-05-06T09:40:57","modified_gmt":"2022-05-06T06:40:57","slug":"virus-found-in-pig-heart-used-in-human-transplant","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/virus-found-in-pig-heart-used-in-human-transplant\/","title":{"rendered":"#Virus found in pig heart used in human transplant"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a37c6022986c\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a37c6022986c\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/virus-found-in-pig-heart-used-in-human-transplant\/#%E2%80%9CVirus_found_in_pig_heart_used_in_human_transplant%E2%80%9D\" >&#8220;Virus found in pig heart used in human transplant&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CVirus_found_in_pig_heart_used_in_human_transplant%E2%80%9D\"><\/span>&#8220;Virus found in pig heart used in human transplant&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2022\/virus-found-in-pig-hea.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/virus-found-in-pig-hea.jpg\" data-sub-html=\"In this photo provided by the University of Maryland School of Medicine, David Bennett Jr., right, stands next to his father's hospital bed in Baltimore, Md., on Jan. 12, 2022, five days after doctors transplanted a pig heart into Bennett Sr., in a last-ditch effort to save his life. Researchers trying to learn what killed Bennett Sr., the first person to receive a heart transplant from a pig, have discovered signs of an animal virus in the organ but cannot yet say if it played any role in the man\u2019s death. Credit: University of Maryland School of Medicine via AP\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2022\/virus-found-in-pig-hea.jpg\" alt=\"Virus found in pig heart used in human transplant\" title=\"In this photo provided by the University of Maryland School of Medicine, David Bennett Jr., right, stands next to his father's hospital bed in Baltimore, Md., on Jan. 12, 2022, five days after doctors transplanted a pig heart into Bennett Sr., in a last-ditch effort to save his life. Researchers trying to learn what killed Bennett Sr., the first person to receive a heart transplant from a pig, have discovered signs of an animal virus in the organ but cannot yet say if it played any role in the man\u2019s death. Credit: University of Maryland School of Medicine via AP\" width=\"800\" height=\"530\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                In this photo provided by the University of Maryland School of Medicine, David Bennett Jr., right, stands next to his father&#8217;s hospital bed in Baltimore, Md., on Jan. 12, 2022, five days after doctors transplanted a pig heart into Bennett Sr., in a last-ditch effort to save his life. Researchers trying to learn what killed Bennett Sr., the first person to receive a heart transplant from a pig, have discovered signs of an animal virus in the organ but cannot yet say if it played any role in the man\u2019s death. Credit: University of Maryland School of Medicine via AP<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>Researchers trying to learn what killed the first person to receive a heart transplant from a pig have discovered the organ harbored an animal virus but cannot yet say if it played any role in the man&#8217;s death.\n                                                <\/p>\n<p>                                                                                A Maryland man, 57-year-old David Bennett Sr., died in March, two months after the groundbreaking experimental transplant. University of Maryland doctors said Thursday they found an unwelcome surprise\u2014viral DNA inside the pig heart. They did not find signs that this bug, called porcine cytomegalovirus, was causing an active infection.<\/p>\n<p>But a major worry about animal-to-human transplants is the risk that it could introduce new kinds of infections to people.<\/p>\n<p>Because some viruses are &#8220;latent,&#8221; meaning they lurk without causing disease, &#8220;it could be a hitchhiker,&#8221; Dr. Bartley Griffith, the surgeon who performed Bennett&#8217;s transplant, told The Associated Press.<\/p>\n<p>Still, development is under way of more sophisticated tests to &#8220;make sure that we don&#8217;t miss these kinds of viruses,&#8221; added Dr. Muhammad Mohiuddin, scientific director of the university&#8217;s xenotransplant program.<\/p>\n<p>The animal virus was first reported by MIT <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/technology\/\" data-internallinksmanager029f6b8e52c=\"4\" title=\"Technology\" target=\"_blank\" rel=\"noopener\">Technology<\/a> Review, citing a scientific presentation Griffith gave to the American Society of Transplantation last month.<\/p>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2022\/virus-found-in-pig-hea-1.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/virus-found-in-pig-hea-1.jpg\" data-sub-html=\"In this photo provided by the University of Maryland School of Medicine, members of the surgical team show the pig heart for transplant into patient David Bennett in Baltimore on Friday, Jan. 7, 2022. Researchers trying to learn what killed Bennett, the first person to receive a heart transplant from a pig, have discovered signs of an animal virus in the organ but cannot yet say if it played any role in the man\u2019s death. Credit: Mark Teske\/University of Maryland School of Medicine via AP, File\">\n<figure class=\"article-img text-center\">\n            <img decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800\/2022\/virus-found-in-pig-hea-1.jpg\" alt=\"Virus found in pig heart used in human transplant\"\/><figcaption class=\"text-left text-darken text-truncate text-low-up mt-3\">\n                In this photo provided by the University of Maryland School of Medicine, members of the surgical team show the pig heart for transplant into patient David Bennett in Baltimore on Friday, Jan. 7, 2022. Researchers trying to learn what killed Bennett, the first person to receive a heart transplant from a pig, have discovered signs of an animal virus in the organ but cannot yet say if it played any role in the man\u2019s death. Credit: Mark Teske\/University of Maryland School of Medicine via AP, File<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>For decades, doctors have tried using animal organs to save human lives without success. Bennett, who was dying and ineligible for a human heart transplant, underwent the last-ditch operation using a heart from a pig genetically modified to lower the risk that his immune system would rapidly reject such a foreign organ.<\/p>\n<p>The Maryland team said the donor pig was healthy, had passed testing required by the Food and Drug Administration to check for infections, and was raised in a facility designed to prevent animals from spreading infections. Revivicor, the company that provided the animal, declined to comment.<\/p>\n<p>Griffith said his patient, while very ill, had been recovering fairly well from the transplant when one morning he woke up worse, with symptoms similar to an infection. Doctors ran numerous tests to try to understand the cause, and gave Bennett a variety of antibiotics, antiviral medication and an immune-boosting treatment. But the pig heart became swollen, filled with fluid and eventually quit functioning.<\/p>\n<p>&#8220;What was the virus doing, if anything, that might have caused the swelling in his heart?&#8221; Griffith asked. &#8220;Honestly we don&#8217;t know.&#8221;<\/p>\n<p>The reaction also didn&#8217;t <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ear to be a typical organ rejection, he said, noting the investigation still is underway.<\/p>\n<p>Meanwhile doctors at other medical centers around the country have been experimenting with animal organs in donated human bodies and are anxious to attempt formal studies in living patients soon. It&#8217;s not clear how the pig virus will affect those plans.\n                                                                                                                        <\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                                                                        Pig heart recipient continues to recover from transplant\n                                                                                    <\/p><\/div>\n<hr class=\"mb-4\"\/>\n<p class=\"article-main__note mt-4\">\n                                                \u00a9 2022 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission.<\/p>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Virus found in pig heart used in human transplant (2022, May  6)<br \/>\n                                                 retrieved  6 May 2022<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-05-virus-pig-heart-human-transplant.html<\/p>\n<p>                                            This document is subject to copyright. 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