{"id":452315,"date":"2022-05-25T00:23:02","date_gmt":"2022-05-24T21:23:02","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/why-are-male-mice-afraid-of-bananas\/"},"modified":"2022-05-25T00:23:02","modified_gmt":"2022-05-24T21:23:02","slug":"why-are-male-mice-afraid-of-bananas","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/why-are-male-mice-afraid-of-bananas\/","title":{"rendered":"#Why are male mice afraid of bananas?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a36c4495550a\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a36c4495550a\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/why-are-male-mice-afraid-of-bananas\/#%E2%80%9CWhy_are_male_mice_afraid_of_bananas%E2%80%9D\" >&#8220;Why are male mice afraid of bananas?&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CWhy_are_male_mice_afraid_of_bananas%E2%80%9D\"><\/span>&#8220;Why are male mice afraid of bananas?&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2022\/why-are-male-mice-afra.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/why-are-male-mice-afra.jpg\" data-sub-html=\"Olfactory exposure to late-pregnant and lactating mice produces analgesia in male but not female mice in the radiant heat paw-withdrawal test. (A and B) Latency to hind paw-withdrawal (s) from radiant heat of male (A) and female (B) mice before (Pre) and during (Post) exposure to stimulus mice of various reproductive conditions: na\u00efve male, na\u00efve female (NF), early pregnant (EP), late pregnant (LP), lactating (Lact.) [with pups present (+ pups), without pups present (\u2212 pups), and with pups removed 24 hours before (\u2212 pups 24 hours)], and after weaning. (C and D) Change (\u0394) in hind paw-withdrawal latency (Post-Pre) in all stimulus conditions shown in graphs (A) and (B) in male (C) and female (D) mice. Positive values (green) represent analgesia; negative values (pink) represent hyperalgesia. In all graphs, individual data are shown (n = 10 to 12 mice per sex per condition); black bars represent means \u00b1 SEM. *P &lt; 0.05, ***P &lt; 0.001 compared to zero by two-tailed one-sample Student\u2019s t test; asterisks are shown in red if the t test result is still statistically significant at P &lt; 0.05 after correction for multiple comparisons. Credit: &lt;i&gt;Science Advances&lt;\/i&gt; (2022). DOI: 10.1126\/sciadv.abi9366\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2022\/why-are-male-mice-afra.jpg\" alt=\"Why are male mice afraid of bananas?\" title=\"Olfactory exposure to late-pregnant and lactating mice produces analgesia in male but not female mice in the radiant heat paw-withdrawal test. (A and B) Latency to hind paw-withdrawal (s) from radiant heat of male (A) and female (B) mice before (Pre) and during (Post) exposure to stimulus mice of various reproductive conditions: na\u00efve male, na\u00efve female (NF), early pregnant (EP), late pregnant (LP), lactating (Lact.) [with pups present (+ pups), without pups present (\u2212 pups), and with pups removed 24 hours before (\u2212 pups 24 hours)], and after weaning. (C and D) Change (\u0394) in hind paw-withdrawal latency (Post-Pre) in all stimulus conditions shown in graphs (A) and (B) in male (C) and female (D) mice. Positive values (green) represent analgesia; negative values (pink) represent hyperalgesia. In all graphs, individual data are shown (n = 10 to 12 mice per sex per condition); black bars represent means \u00b1 SEM. *P &lt; 0.05, ***P &lt; 0.001 compared to zero by two-tailed one-sample Student\u2019s t test; asterisks are shown in red if the t test result is still statistically significant at P &lt; 0.05 after correction for multiple comparisons. Credit: &lt;i&gt;Science Advances&lt;\/i&gt; (2022). DOI: 10.1126\/sciadv.abi9366\" width=\"800\" height=\"530\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                Olfactory exposure to late-pregnant and lactating mice produces analgesia in male but not female mice in the radiant heat paw-withdrawal test. (A and B) Latency to hind paw-withdrawal (s) from radiant heat of male (A) and female (B) mice before (Pre) and during (Post) exposure to stimulus mice of various reproductive conditions: na\u00efve male, na\u00efve female (NF), early pregnant (EP), late pregnant (LP), lactating (Lact.) [with pups present (+ pups), without pups present (\u2212 pups), and with pups removed 24 hours before (\u2212 pups 24 hours)], and after weaning. (C and D) Change (\u0394) in hind paw-withdrawal latency (Post-Pre) in all stimulus conditions shown in graphs (A) and (B) in male (C) and female (D) mice. Positive values (green) represent analgesia; negative values (pink) represent hyperalgesia. In all graphs, individual data are shown (n = 10 to 12 mice per sex per condition); black bars represent means \u00b1 SEM. *P <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">Science<\/a> Advances (2022). DOI: 10.1126\/sciadv.abi9366<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>Researchers from McGill University have identified a form of chemical signaling in mice to defend their offspring. The researchers found that proximity to pregnant and lactating female mice increased stress hormones in males and even decreased their sensitivity to pain.<\/p>\n<section class=\"article-banner first-banner ads-336x280\">\n         <!-- \/4988204\/Phys_Story_InText_Box --><\/p>\n<\/section>\n<p>&#8220;The findings have important implications for improving the reliability and reproducibility of experiments involving mice. This is yet another example of a previously unknown factor in the lab environment that can affect the results of scientific studies,&#8221; says Jeffrey Mogil, a Professor in the Department of Psychology at McGill University and E. P. Taylor Chair in Pain Studies.<\/p>\n<p>According to co-author Sarah Rosen, &#8220;what is likely h<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ening is that female mice are signaling to males who might be considering attacking their babies that they will defend them vigorously. It&#8217;s the threat of the possible upcoming fight that causes the stress.&#8221;<\/p>\n<p>&#8220;Mice have richer communication with one another than we think; it&#8217;s just that a lot of it&#8217;s through smell,&#8221; says Mogil. The researchers started looking for the olfactory chemical responsible. Several odorants were identified, but one, n-pentyl acetate, which is released in the urine of pregnant and lactating female mice, was especially effective at producing stress in male mice. <\/p>\n<p>&#8220;Curiously, n-pentyl acetate is also responsible for the unique smell of bananas. After a quick <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/trip-and-travel\/\" data-internallinksmanager029f6b8e52c=\"10\" title=\"Trip &amp; Travel\" target=\"_blank\" rel=\"noopener\">trip<\/a> to the supermarket for some banana oil, we were able to confirm that the smell of banana extract stressed the male mice just as much as the pregnant females,&#8221; says co-author Lucas Lima.     <\/p>\n<p>The finding represents a breakthrough in the science of mammalian <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/social-mediaa\/\" data-internallinksmanager029f6b8e52c=\"1\" title=\"Social Media\" target=\"_blank\" rel=\"noopener\">social<\/a> signaling. &#8220;There are a number of examples of male-to-female olfactory signaling in rodents, but far fewer examples of female-to-male signaling, especially outside of the realm of sexual behavior,&#8221; says Mogil.<\/p>\n<p>&#8220;Olfactory exposure to late-pregnant and lactating mice causes stress-induced analgesia in male mice&#8221; by Sarah Rosen et al. was published in <i>Science Advances<\/i>.<\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                            <a rel=\"nofollow noopener\" target=\"_blank\" class=\"text-medium text-info mt-2 d-inline-block\" href=\"https:\/\/medicalxpress.com\/news\/2016-07-neuroscientists-female-mice.html\">Neuroscientists says it is time to start using more female mice for testing<\/a>\n                                        <\/div>\n<hr class=\"mb-4\"\/>\n<div class=\"article-main__more p-4\">\n                                                                                                <strong>More information:<\/strong><br \/>\n                                                Sarah F. Rosen et al, Olfactory exposure to late-pregnant and lactating mice causes stress-induced analgesia in male mice, <i>Science Advances<\/i> (2022).  <a rel=\"nofollow noopener\" target=\"_blank\" data-doi=\"1\" href=\"https:\/\/dx.doi.org\/10.1126\/sciadv.abi9366\">DOI: 10.1126\/sciadv.abi9366<\/a><\/p><\/div>\n<div class=\"d-inline-block text-medium my-4\">\n                                                Provided by<br \/>\n                                                                                                    McGill University<br \/>\n                                                                                                        <a rel=\"nofollow noopener\" target=\"_blank\" class=\"icon_open\" href=\"http:\/\/www.mcgill.ca\/\"><br \/>\n                                                        <svg>\n                                                            <use href=\"https:\/\/phys.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/>\n                                                        <\/svg><br \/>\n                                                    <\/a><\/p><\/div>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Why are male mice afraid of bananas? (2022, May 24)<br \/>\n                                                 retrieved 24 May 2022<br \/>\n                                                 from https:\/\/phys.org\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-05-male-mice-bananas.html<\/p>\n<p>                                            This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no<br \/>\n                                            part may be reproduced without the written permission. The content is provided for information purposes only.<\/p><\/div>\n<\/p><\/div>\n<p><script id=\"facebook-jssdk\" async=\"\" src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong>\n<\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Like this articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/science\/\" target=\"_blank\" rel=\"noopener\">Science category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/phys.org\/news\/2022-05-male-mice-bananas.html\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Why are male mice afraid of bananas?&#8221; Olfactory exposure to late-pregnant and lactating mice produces analgesia in male but not female mice in the radiant heat paw-withdrawal test. (A and B) Latency to hind paw-withdrawal (s) from radiant heat of male (A) and female (B) mice before (Pre) and during (Post) exposure to stimulus mice&#8230;<\/p>\n","protected":false},"author":1,"featured_media":452316,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/why-are-male-mice-afra.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-452315","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/452315","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=452315"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/452315\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/452316"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=452315"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=452315"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=452315"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}