{"id":465637,"date":"2022-06-20T12:00:01","date_gmt":"2022-06-20T09:00:01","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/single-brain-scan-can-diagnose-alzheimers-disease\/"},"modified":"2022-06-20T12:00:01","modified_gmt":"2022-06-20T09:00:01","slug":"single-brain-scan-can-diagnose-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/single-brain-scan-can-diagnose-alzheimers-disease\/","title":{"rendered":"#Single brain scan can diagnose Alzheimer&#8217;s disease"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a26baf36c6de\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a26baf36c6de\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/single-brain-scan-can-diagnose-alzheimers-disease\/#%E2%80%9CSingle_brain_scan_can_diagnose_Alzheimers_disease%E2%80%9D\" >&#8220;Single brain scan can diagnose Alzheimer&#8217;s disease&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CSingle_brain_scan_can_diagnose_Alzheimers_disease%E2%80%9D\"><\/span>&#8220;Single brain scan can diagnose Alzheimer&#8217;s disease&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2017\/alzheimersdi.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2017\/alzheimersdi.jpg\" data-sub-html=\"PET scan of a human brain with Alzheimer's disease. Credit: public domain\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2017\/alzheimersdi.jpg\" alt=\"Alzheimer's disease\" title=\"PET scan of a human brain with Alzheimer's disease. Credit: public domain\" width=\"775\" height=\"530\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                PET scan of a human brain with Alzheimer&#8217;s disease. Credit: public domain<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>The research uses machine learning <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/technology\/\" data-internallinksmanager029f6b8e52c=\"4\" title=\"Technology\" target=\"_blank\" rel=\"noopener\">technology<\/a> to look at structural features within the brain, including in regions not previously associated with Alzheimer&#8217;s. The advantage of the technique is its simplicity and the fact that it can identify the disease at an early stage when it can be very difficult to diagnose.\n                                                <\/p>\n<p>                                                                                Although there is no cure for Alzheimer&#8217;s disease, getting a diagnosis quickly at an early stage helps patients. It allows them to access help and support, get treatment to manage their symptoms and plan for the future. Being able to accurately identify patients at an early stage of the disease will also help researchers to understand the brain changes that trigger the disease, and support development and trials of new treatments.<\/p>\n<p>The research is published in the Nature Portfolio Journal, <i>Communications Medicine<\/i>.<\/p>\n<p>Alzheimer&#8217;s disease is the most common form of dementia, affecting over half a million people in the UK. Although most people with Alzheimer&#8217;s disease develop it after the age of 65, people under this age can develop it too. The most frequent symptoms of dementia are memory loss and difficulties with thinking, problem solving and language. <\/p>\n<p>Doctors currently use a raft of tests to diagnose Alzheimer&#8217;s disease, including memory and cognitive tests and brain scans. The scans are used to check for protein deposits in the brain and shrinkage of the hippocampus, the area of the brain linked to memory. All of these tests can take several weeks, both to arrange and to process.<\/p>\n<p>The new <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>roach requires just one of these\u2014a magnetic resonance imaging (MRI) brain scan taken on a standard 1.5 Tesla machine, which is commonly found in most hospitals.<\/p>\n<p>The researchers adapted an algorithm developed for use in classifying cancer tumors, and applied it to the brain. They divided the brain into 115 regions and allocated 660 different features, such as size, shape and texture, to assess each region. They then trained the algorithm to identify where changes to these features could accurately predict the existence of Alzheimer&#8217;s disease.<br \/>\n                                            <!-- Google middle Adsense block --><\/p>\n<p>Using data from the Alzheimer&#8217;s Disease Neuroimaging Initiative, the team tested their approach on brain scans from over 400 patients with early and later stage Alzheimer&#8217;s, healthy controls and patients with other neurological conditions, including frontotemporal dementia and Parkinson&#8217;s disease. They also tested it with data from over 80 patients undergoing diagnostic tests for Alzheimer&#8217;s at Imperial College Healthcare NHS Trust.<\/p>\n<p>They found that in 98 percent of cases, the MRI-based machine learning system alone could accurately predict whether the patient had Alzheimer&#8217;s disease or not. It was also able to distinguish between early and late-stage Alzheimer&#8217;s with fairly high accuracy, in 79 percent of patients. <\/p>\n<p>Professor Eric Aboagye, from Imperial&#8217;s Department of Surgery and Cancer, who led the research, said: &#8220;Currently no other simple and widely available methods can predict Alzheimer&#8217;s disease with this level of accuracy, so our research is an important step forward. Many patients who present with Alzheimer&#8217;s at memory clinics do also have other neurological conditions, but even within this group our system could pick out those patients who had Alzheimer&#8217;s from those who did not.<\/p>\n<p>&#8220;Waiting for a diagnosis can be a horrible experience for patients and their families. If we could cut down the amount of time they have to wait, make diagnosis a simpler process, and reduce some of the uncertainty, that would help a great deal. Our new approach could also identify early-stage patients for clinical trials of new drug treatments or lifestyle changes, which is currently very hard to do.&#8221;<\/p>\n<p>The new system spotted changes in areas of the brain not previously associated with Alzheimer&#8217;s disease, including the cerebellum (the part of the brain that coordinates and regulates physical activity) and the ventral diencephalon (linked to the senses, sight and hearing). This opens up potential new avenues for research into these areas and their links to Alzheimer&#8217;s disease.<\/p>\n<p>Dr. Paresh Malhotra, who is a consultant neurologist at Imperial College Healthcare NHS Trust and a researcher in Imperial&#8217;s Department of Brain <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">Science<\/a>s, said: &#8220;Although neuroradiologists already interpret MRI scans to help diagnose Alzheimer&#8217;s, there are likely to be features of the scans that aren&#8217;t visible, even to specialists. Using an algorithm able to select texture and subtle structural features in the brain that are affected by Alzheimer&#8217;s could really enhance the information we can gain from standard imaging techniques.&#8221;\n                                                                                                                        <\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                                                                        New Alzheimer&#8217;s biomarker may facilitate rapid diagnosis\n                                                                                    <\/p><\/div>\n<hr class=\"mb-4\"\/>\n<div class=\"article-main__more p-4\">\n                                                                                                <strong>More information:<\/strong><br \/>\n                                                A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer&#8217;s disease, <i>Communications Medicine<\/i> (2022).<\/p><\/div>\n<div class=\"d-inline-block text-medium my-4\">\n                                                Provided by<br \/>\n                                                                                                    Imperial College London<br \/>\n                                                                                                        <a rel=\"nofollow noopener\" target=\"_blank\" class=\"icon_open\" href=\"http:\/\/www3.imperial.ac.uk\/\"><br \/>\n                                                        <svg>\n                                                            <use href=\"https:\/\/medx.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/>\n                                                        <\/svg><br \/>\n                                                    <\/a><\/p><\/div>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>\n                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Single brain scan can diagnose Alzheimer&#8217;s disease (2022, June 20)<br \/>\n                                                 retrieved 20 June 2022<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-06-brain-scan-alzheimer-disease.html<\/p>\n<p>                                            This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no<br \/>\n                                            part may be reproduced without the written permission. The content is provided for information purposes only.<\/p><\/div>\n<\/p><\/div>\n<p><script id=\"facebook-jssdk\" async=\"\" src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong>\n<\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Like this articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/science\/\" target=\"_blank\" rel=\"noopener\">Science category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/medicalxpress.com\/news\/2022-06-brain-scan-alzheimer-disease.html\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Single brain scan can diagnose Alzheimer&#8217;s disease&#8221; PET scan of a human brain with Alzheimer&#8217;s disease. Credit: public domain The research uses machine learning technology to look at structural features within the brain, including in regions not previously associated with Alzheimer&#8217;s. The advantage of the technique is its simplicity and the fact that it can&#8230;<\/p>\n","protected":false},"author":1,"featured_media":465638,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2017\/alzheimersdi.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-465637","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/465637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=465637"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/465637\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/465638"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=465637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=465637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=465637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}