{"id":476867,"date":"2022-07-22T22:41:26","date_gmt":"2022-07-22T19:41:26","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/dynamic-mental-illness-indicators-caught-by-advanced-ai-in-brain-imaging\/"},"modified":"2022-07-22T22:41:26","modified_gmt":"2022-07-22T19:41:26","slug":"dynamic-mental-illness-indicators-caught-by-advanced-ai-in-brain-imaging","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/dynamic-mental-illness-indicators-caught-by-advanced-ai-in-brain-imaging\/","title":{"rendered":"#Dynamic mental illness indicators caught by advanced AI in brain imaging"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6aee5a2a24eac\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6aee5a2a24eac\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/dynamic-mental-illness-indicators-caught-by-advanced-ai-in-brain-imaging\/#%E2%80%9CDynamic_mental_illness_indicators_caught_by_advanced_AI_in_brain_imaging%E2%80%9D\" >&#8220;Dynamic mental illness indicators caught by advanced AI in brain imaging&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CDynamic_mental_illness_indicators_caught_by_advanced_AI_in_brain_imaging%E2%80%9D\"><\/span>&#8220;Dynamic mental illness indicators caught by advanced AI in brain imaging&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2021\/4-brain.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2021\/4-brain.jpg\" data-sub-html=\"Credit: Pixabay\/CC0 Public Domain\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2021\/4-brain.jpg\" alt=\"brain\" title=\"Credit: Pixabay\/CC0 Public Domain\" width=\"800\" height=\"300\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                Credit: Pixabay\/CC0 Public Domain<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>New research by Georgia State University&#8217;s TReNDS Center may lead to early diagnosis of devastating conditions such as Alzheimer&#8217;s disease, schizophrenia and autism\u2014in time to help prevent and more easily treat these disorders. In a new study published in <i>Scientific Reports<\/i> a team of seven scientists from Georgia State built a sophisticated computer program that was able to comb through massive amounts of brain imaging data and discover novel patterns linked to mental health conditions. The brain imaging data came from scans using functional magnetic resonance imaging (fMRI), which measures dynamic brain activity by detecting tiny changes in blood flow.\n                                                <\/p>\n<p>                                                                                &#8220;We built artificial intelligence models to interpret the large amounts of information from fMRI,&#8221; said Sergey Plis, associate professor of computer <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">science<\/a> and neuroscience at Georgia State, and lead author on the study.<\/p>\n<p>He compared this kind of dynamic imaging to a movie\u2014as opposed to a snapshot such as an X-ray or, the more common structural MRI\u2014and noted &#8220;the available data is so much larger, so much richer than a blood test or a regular MRI. But that&#8217;s the challenge\u2014that huge amount of data is hard to interpret.&#8221;<\/p>\n<p>In addition, fMRI&#8217;s on these specific conditions are expensive, and not easy to obtain. Using an artificial intelligence model, however, regular fMRI&#8217;s can be data mined. And those are available in large numbers.<\/p>\n<p>&#8220;There are large datasets available in individuals without a known clinical disorder,&#8221; explains Vince Calhoun, Founding Director of the TReNDS Center, and one of the study&#8217;s authors. Using these large but unrelated available datasets improved the model&#8217;s performance on smaller specific datasets.<\/p>\n<p>&#8220;New patterns emerged that we could definitively link to each of the three brain disorders,&#8221; Calhoun said.<\/p>\n<p>The AI models were first trained on a dataset including over 10,000 individuals to learn to understand basic fMRI imaging and brain function. The researchers then used multi-site data sets of over 1200 individuals including those with autism spectrum disorder, schizophrenia, and Alzheimer&#8217;s disease.<\/p>\n<p>How does it work? It&#8217;s a bit like <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/social-mediaa\/\" data-internallinksmanager029f6b8e52c=\"1\" title=\"Social Media\" target=\"_blank\" rel=\"noopener\">Facebook<\/a>, YouTube or Amazon learning about you from your online behavior, and beginning to be able to predict future behavior, likes and dislikes. The computer software was even able to home in on the &#8220;moment&#8221; when the brain imaging data was most likely linked to the mental disorder in question.<\/p>\n<p>To make these findings clinically useful, they will need to be <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>lied before a disorder manifests.<\/p>\n<p>&#8220;If we can find markers for and predict Alzheimer&#8217;s risk in a 40-year-old,&#8221; Calhoun said, &#8220;we might be able to do something about it.&#8221;<\/p>\n<p>Similarly, if schizophrenia risks can be predicted before there are actual changes in brain structure, there may be ways to offer better or more effective treatments.<\/p>\n<p>&#8220;Even if we know from other testing or family history that someone is at risk of a disorder such as Alzheimer&#8217;s, we are still unable to predict when exactly it will occur,&#8221; Calhoun said. &#8220;Brain imaging could narrow down that time window, by catching the relevant patterns when they do show up before clinical disease is apparent.&#8221;<\/p>\n<p>&#8220;The vision is that we collect a large imaging dataset, our AI models pore over it, and show us what they learned about certain disorders,&#8221; Plis said. &#8220;We are building systems to discover new knowledge we could not discover on our own.&#8221;<\/p>\n<p>&#8220;Our goal,&#8221; said Md Mahfuzur Rahman, first author on the study and a doctoral student in computer science at Georgia State, &#8220;is to bridge big worlds and big datasets with small worlds and disease-specific datasets and move towards markers relevant for clinical decisions.&#8221;\n                                                                                                                        <\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                                                                        A multi-site, multi-disorder, resting-state magnetic resonance image database\n                                                                                    <\/p><\/div>\n<hr class=\"mb-4\"\/>\n<div class=\"article-main__more p-4\">\n                                                                                                <strong>More information:<\/strong><br \/>\n                                                Md. Mahfuzur Rahman et al, Interpreting models interpreting brain dynamics, <i>Scientific Reports<\/i> (2022).  <a rel=\"nofollow noopener\" target=\"_blank\" data-doi=\"1\" href=\"https:\/\/dx.doi.org\/10.1038\/s41598-022-15539-2\">DOI: 10.1038\/s41598-022-15539-2<\/a><\/p><\/div>\n<div class=\"d-inline-block text-medium my-4\">\n                                                Provided by<br \/>\n                                                                                                    Georgia State University<br \/>\n                                                                                                        <a rel=\"nofollow noopener\" target=\"_blank\" class=\"icon_open\" href=\"http:\/\/www.gsu.edu\/\"><br \/>\n                                                        <svg>\n                                                            <use href=\"https:\/\/medx.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/>\n                                                        <\/svg><br \/>\n                                                    <\/a><\/p><\/div>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>\n                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Dynamic mental illness indicators caught by advanced AI in brain imaging (2022, July 22)<br \/>\n                                                 retrieved 22 July 2022<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-07-dynamic-mental-illness-indicators-caught.html<\/p>\n<p>                                            This document is subject to copyright. 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In a new study published in Scientific&#8230;<\/p>\n","protected":false},"author":1,"featured_media":476868,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2021\/4-brain.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-476867","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/476867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=476867"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/476867\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/476868"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=476867"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=476867"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=476867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}