{"id":482195,"date":"2022-08-07T18:00:01","date_gmt":"2022-08-07T15:00:01","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/scientists-revive-cells-and-organs-in-dead-pigs\/"},"modified":"2022-08-07T18:00:01","modified_gmt":"2022-08-07T15:00:01","slug":"scientists-revive-cells-and-organs-in-dead-pigs","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/scientists-revive-cells-and-organs-in-dead-pigs\/","title":{"rendered":"#Scientists revive cells and organs in dead pigs"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6af3a92f7db5a\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" 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ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/scientists-revive-cells-and-organs-in-dead-pigs\/#%E2%80%9CScientists_revive_cells_and_organs_in_dead_pigs%E2%80%9D\" >&#8220;Scientists revive cells and organs in dead pigs&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CScientists_revive_cells_and_organs_in_dead_pigs%E2%80%9D\"><\/span>&#8220;Scientists revive cells and organs in dead pigs&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2022\/a-new-technique-can-re.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/2022\/a-new-technique-can-re.jpg\" data-sub-html=\"A new technique can revive the cells and organs of pigs an hour after death, offering hope for future human organ donations.\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2022\/a-new-technique-can-re.jpg\" alt=\"A new technique can revive the cells and organs of pigs an hour after death, offering hope for future human organ donations\" title=\"A new technique can revive the cells and organs of pigs an hour after death, offering hope for future human organ donations.\" width=\"800\" height=\"530\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                A new technique can revive the cells and organs of pigs an hour after death, offering hope for future human organ donations.<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>Scientists announced Wednesday they have restored blood flow and cell function throughout the bodies of pigs that were dead for an hour, in a breakthrough experts say could mean we need to update the definition of death itself.\n                                                <\/p>\n<p>                                                                                The discovery raised hopes for a range of future medical uses in humans, the most im<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/social-mediaa\/\" data-internallinksmanager029f6b8e52c=\"1\" title=\"Social Media\" target=\"_blank\" rel=\"noopener\">media<\/a>te being that it could help organs last longer, potentially saving the lives of thousands of people worldwide in need of transplants.<\/p>\n<p>However it could also spur debate about the ethics of such procedures\u2014particularly after some of the ostensibly dead pigs startled the scientists by making sudden head movements during the experiment.<\/p>\n<p>The US-based team stunned the scientific community in 2019 by managing to restore cell function in the brains of pigs hours after they had been decapitated.<\/p>\n<p>For the latest research, published in the journal <i>Nature<\/i>, the team sought to expand this technique to the entire body.<\/p>\n<p>They induced a heart attack in the anesthetized pigs, which stopped blood flowing through the bodies.<\/p>\n<p>This deprives the body&#8217;s cells of oxygen\u2014and without oxygen, cells in mammals die.<\/p>\n<p>The pigs then sat dead for an hour.<\/p>\n<p><b>&#8216;Demise of cells can be halted&#8217;<\/b><\/p>\n<p>The scientists then pumped the bodies with a liquid containing the pigs&#8217; own blood, as well as a synthetic form of hemoglobin\u2014the protein that carries oxygen in red blood cells\u2014and drugs that protect cells and prevent blood clots.<\/p>\n<p>Blood started circulating again and many cells began functioning including in vital organs such as the heart, liver and kidney, for the next six hours of the experiment.<\/p>\n<p>&#8220;These cells were functioning hours after they should not have been\u2014what this tells us is that the demise of cells can be halted,&#8221; Nenad Sestan, the study&#8217;s senior author and a researcher at Yale University, told journalists.<\/p>\n<p>Co-lead author David Andrijevic, also from Yale, told AFP the team hopes the technique, called OrganEx, &#8220;can be used to salvage organs&#8221;.<br \/>\n                                            <!-- Google middle Adsense block --><\/p>\n<p>OrganEx could also make new forms of surgery possible as it creates &#8220;more medical wiggle room in cases with no circulation to fix things,&#8221; said Anders Sandberg of Oxford University&#8217;s Future of Humanity Institute.<\/p>\n<p>The technique could potentially also be used to resuscitate people. However this could increase the risk of bringing back patients to a point where they are unable to live without life support\u2014tr<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ed on what is called the &#8220;bridge to nowhere,&#8221; Brendan Parent, a bioethicist at the NYU Grossman School of Medicine, said in a linked comment in Nature.<\/p>\n<p><b>Could death be treatable?<\/b><\/p>\n<p>Sam Parnia of the NYU Grossman School of Medicine said it was &#8220;a truly remarkable and incredibly significant study&#8221;.<\/p>\n<p>It showed that death was not black and white but rather a &#8220;biological process that remains treatable and reversible for hours after it has occurred&#8221;, he said.<\/p>\n<p>Benjamin Curtis, a philosopher focused on ethics at the UK&#8217;s Nottingham Trent University, said the definition of death may need updating because it hinges on the concept of irreversibility.<\/p>\n<p>&#8220;This research shows that many processes that we thought were irreversible are not in fact irreversible, and so on the current medical definition of death a person may not be truly dead until hours after their bodily functions have stopped,&#8221; he told AFP.<\/p>\n<p>&#8220;Indeed, there may be bodies lying in morgues right now that haven&#8217;t yet &#8216;died&#8217;, if we take the current definition as valid.&#8221;<\/p>\n<p>During the experiment, pretty much all of the OrganEx pigs made powerful movements with their head and neck, said Stephen Latham, a Yale ethicist and study co-author.<\/p>\n<p>&#8220;It was quite startling for the people in the room,&#8221; he told journalists.<\/p>\n<p>He emphasized that while it was not known what caused the movement, at no point was any electrical activity recorded in the pigs&#8217; brains, showing that they never regained consciousness after death.<\/p>\n<p>While there was a &#8220;little burst&#8221; on the EEG machine measuring brain activity at the time of the movement, Latham said that was probably caused by the shifting of the head affecting the recording.<\/p>\n<p>However Curtis said the movement was a &#8220;major concern&#8221; because recent neuro<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">science<\/a> research has suggested that &#8220;conscious experience can continue even when electrical activity in the brain cannot be measured&#8221;.<\/p>\n<p>&#8220;So it is possible that this technique did in fact cause the subject pigs to suffer, and would cause human beings to suffer were it to be used on them,&#8221; he added, calling for more research.\n                                                                                                                        <\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                                                                        Newly developed <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/technology\/\" data-internallinksmanager029f6b8e52c=\"4\" title=\"Technology\" target=\"_blank\" rel=\"noopener\">technology<\/a> restores cell, organ function in pigs after death\n                                                                                    <\/p><\/div>\n<hr class=\"mb-4\"\/>\n<div class=\"article-main__more p-4\">\n                                                                                                <strong>More information:<\/strong><br \/>\n                                                Nenad Sestan, Cellular recovery after prolonged warm ischaemia of the whole body, <i>Nature<\/i> (2022).  <a rel=\"nofollow noopener\" target=\"_blank\" data-doi=\"1\" href=\"https:\/\/dx.doi.org\/10.1038\/s41586-022-05016-1\">DOI: 10.1038\/s41586-022-05016-1<\/a>. <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41586-022-05016-1\">www.nature.com\/articles\/s41586-022-05016-1<\/a><\/p><\/div>\n<p class=\"article-main__note mt-4\">\n                                                \u00a9 2022 AFP<\/p>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Scientists revive cells and organs in dead pigs (2022, August  7)<br \/>\n                                                 retrieved  7 August 2022<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-08-scientists-revive-cells-dead-pigs.html<\/p>\n<p>                                            This document is subject to copyright. 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Scientists announced Wednesday they have restored blood flow and cell function throughout the bodies of pigs that were dead for an hour, in a breakthrough&#8230;<\/p>\n","protected":false},"author":1,"featured_media":482196,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/2022\/a-new-technique-can-re.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-482195","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/482195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=482195"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/482195\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/482196"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=482195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=482195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=482195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}