{"id":494299,"date":"2022-09-19T16:13:21","date_gmt":"2022-09-19T13:13:21","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/study-finds-mechanical-circulatory-support-and-renal-perfusion-success-with-the-modulheart-device\/"},"modified":"2022-09-19T16:13:21","modified_gmt":"2022-09-19T13:13:21","slug":"study-finds-mechanical-circulatory-support-and-renal-perfusion-success-with-the-modulheart-device","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/study-finds-mechanical-circulatory-support-and-renal-perfusion-success-with-the-modulheart-device\/","title":{"rendered":"#Study finds mechanical circulatory support and renal perfusion success with the ModulHeart device"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a3be51587da6\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a3be51587da6\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/study-finds-mechanical-circulatory-support-and-renal-perfusion-success-with-the-modulheart-device\/#%E2%80%9CStudy_finds_mechanical_circulatory_support_and_renal_perfusion_success_with_the_ModulHeart_device%E2%80%9D\" >&#8220;Study finds mechanical circulatory support and renal perfusion success with the ModulHeart device&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CStudy_finds_mechanical_circulatory_support_and_renal_perfusion_success_with_the_ModulHeart_device%E2%80%9D\"><\/span>&#8220;Study finds mechanical circulatory support and renal perfusion success with the ModulHeart device&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2022\/study-finds-mechanical.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/study-finds-mechanical.jpg\" data-sub-html=\"Graphical abstract. Credit: &lt;i&gt;Journal of the Society for Cardiovascular Angiography &amp; Interventions&lt;\/i&gt; (2022). DOI: 10.1016\/j.jscai.2022.100449\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2022\/study-finds-mechanical.jpg\" alt=\"Study finds mechanical circulatory support and renal perfusion success with the ModulHeart device\" title=\"Graphical abstract. Credit: &lt;i&gt;Journal of the Society for Cardiovascular Angiography &amp; Interventions&lt;\/i&gt; (2022). DOI: 10.1016\/j.jscai.2022.100449\" width=\"800\" height=\"450\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                Graphical abstract. Credit: <i>Journal of the Society for Cardiovascular Angiography &amp; Interventions<\/i> (2022). DOI: 10.1016\/j.jscai.2022.100449<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>A first-in-human (FIH) study using the ModulHeart device (Puzzle Medical Devices Inc.) has demonstrated significant improvement in cardiac output, left ventricular end diastolic pressure, and urine output in patients with heart failure or undergoing high-risk percutaneous coronary intervention (PCI). The findings were presented today during the 34th Transcatheter Cardiovascular Therapeutics (TCT) annual scientific symposium and simultaneously published in the <i>Journal of the Society for Cardiovascular Angiography &amp; Interventions<\/i>.\n                                                <\/p>\n<p>                                                                                There are limited percutaneous hemodynamic support options for patients with heart failure or undergoing high-risk PCI. Current <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>roved devices have limitations that lead to an increase in mortality, morbidity, and higher costs. The ModulHeart device is a novel modular pump implanted percutaneously, providing hemodynamic support through three endovascular pumps which are inserted in <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/watch-movies-tv-seriess\/\" data-internallinksmanager029f6b8e52c=\"8\" title=\"Watch Movies &amp; TV Series\" target=\"_blank\" rel=\"noopener\">series<\/a> and assembled in parallel into a dedicated self-expandable anchor in the descending aorta.<\/p>\n<p>In June 2022, four patients were enrolled in the FIH study and underwent high-risk PCI with ModulHeart implanted via transfemoral approach. Mean delivery time was eight minutes, support time was 49 minutes, and pump removal time was seven minutes. Under ModulHeart support, cardiac index increased by 25%, central venous pressure decreased by 37%, and left ventricular end diastolic pressure decreased by 78%. Urine output increased by ~9-fold after 15 minutes of support. There was no device malfunction, procedural or device-related adverse events and all patients were alive at 30 days post procedure.<\/p>\n<p>&#8220;The first-in-human experience using the ModulHeart device was extremely positive, showing great cardiorenal support and pump function,&#8221; said Dr. Philippe G\u00e9n\u00e9reux, interventional cardiologist at the Gagnon Cardiovascular Institute at Morristown Medical Center in New Jersey, and senior author of the study.<\/p>\n<p>&#8220;The device was easy to deliver and assemble. Once in place, it provided substantial hemodynamic benefits. I am looking forward to the upcoming studies to reduce congestion in patients with acute decompensated heart failure.&#8221;<\/p>\n<p>The current study was performed among patients undergoing high-risk PCI with some degree of left ventricular dysfunction. The researchers state that future studies will target patients with acute and chronic decompensated heart failure with more profound reduced ejection fraction and requiring hemodynamic support and will also explore longer use of the device during the procedure.\n                                                                                                                        <\/p>\n<hr\/>\n<div class=\"article-main__explore my-4 d-print-none\">\n<p>                                                                                        Mayo Clinic Minute: Heart patients helped by ventricular assist devices\n                                                                                    <\/p><\/div>\n<hr class=\"mb-4\"\/>\n<div class=\"article-main__more p-4\">\n                                                                                                <strong>More information:<\/strong><br \/>\n                                                Gabriel Georges et al, First-in-Human Experience With the ModulHeart Device for Mechanical Circulatory Support and Renal Perfusion, <i>Journal of the Society for Cardiovascular Angiography &amp; Interventions<\/i> (2022).  <a rel=\"nofollow noopener\" target=\"_blank\" data-doi=\"1\" href=\"https:\/\/dx.doi.org\/10.1016\/j.jscai.2022.100449\">DOI: 10.1016\/j.jscai.2022.100449<\/a><\/p><\/div>\n<div class=\"d-inline-block text-medium my-4\">\n                                                Provided by<br \/>\n                                                                                                    Society for Cardiovascular Angiography and Interventions<br \/>\n                                                                                                        <a rel=\"nofollow noopener\" target=\"_blank\" class=\"icon_open\" href=\"http:\/\/www.scai.org\/\"><br \/>\n                                                        <svg>\n                                                            <use href=\"https:\/\/medx.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/>\n                                                        <\/svg><br \/>\n                                                    <\/a><\/p><\/div>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>\n                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Study finds mechanical circulatory support and renal perfusion success with the ModulHeart device (2022, September 19)<br \/>\n                                                 retrieved 19 September 2022<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2022-09-mechanical-circulatory-renal-perfusion-success.html<\/p>\n<p>                                            This document is subject to copyright. 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Credit: Journal of the Society for Cardiovascular Angiography &amp; Interventions (2022). DOI: 10.1016\/j.jscai.2022.100449 A first-in-human (FIH) study using the ModulHeart device (Puzzle Medical Devices Inc.) has demonstrated significant improvement in cardiac output, left ventricular end diastolic pressure, and urine output&#8230;<\/p>\n","protected":false},"author":1,"featured_media":494300,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2022\/study-finds-mechanical.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-494299","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/494299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=494299"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/494299\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/494300"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=494299"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=494299"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=494299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}