{"id":559424,"date":"2023-03-04T14:00:00","date_gmt":"2023-03-04T11:00:00","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/why-concerns-are-rising-about-drug-resistant-shigella-infections\/"},"modified":"2023-03-04T14:00:00","modified_gmt":"2023-03-04T11:00:00","slug":"why-concerns-are-rising-about-drug-resistant-shigella-infections","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/why-concerns-are-rising-about-drug-resistant-shigella-infections\/","title":{"rendered":"#Why concerns are rising about drug-resistant Shigella infections"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a26eadd2dae0\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a26eadd2dae0\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/why-concerns-are-rising-about-drug-resistant-shigella-infections\/#Why_concerns_are_rising_about_drug-resistant_Shigella_infections\" >Why concerns are rising about drug-resistant Shigella infections<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"Why_concerns_are_rising_about_drug-resistant_Shigella_infections\"><\/span>Why concerns are rising about drug-resistant Shigella infections<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><img decoding=\"async\" src=\"https:\/\/thehill.com\/wp-content\/uploads\/sites\/2\/2023\/03\/health-wellness-avoid-drug-resistant-shigella-bacteria-tips.jpg?w=900\" \/><\/p>\n<div>\n<p>The health community is growing more concerned about Shigella bacteria infections that have shown a resistance to drugs. <\/p>\n<p>The Centers for Disease Control and Prevention (CDC) last week issued a health alert for a rise in infections caused by a drug-resistant strain of Shigella, bringing new attention to a pathogen that is likely unfamiliar to many in the United States.<\/p>\n<aside class=\"ad-unit ad-unit--mr1_ab\"><\/aside>\n<p>As the CDC noted in its <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/emergency.cdc.gov\/han\/2023\/han00486.asp\">alert<\/a>, five percent of Shigella cases in 2022 were caused by extensively drug-resistant infections of the bacteria, referred to as XDR infections. This marked an increase from when no cases were considered XDR infections in 2015. <\/p>\n<p>\u201cWe received increased reports of XDR infections from our state health partners in several regions of the U.S. and then we also received multiple communications from physicians, from IV docs in particular, who were inquiring about treatment options for these really challenging cases,\u201d CDC Medical Officer Naeemah Logan told The Hill.<\/p>\n<p>CDC officials said it\u2019s unclear if some regions of the U.S. are seeing more Shigella cases than others as not all regions have the same level of surveillance and reporting data can lag. But the rise in drug resistant Shigella infections is notable.<\/p>\n<p>CDC Medical Officer Louise Francois Watkins noted that XDR infections from other bacterias could take decades to increase from zero to five percent of cases, but Shigella accomplished this in just a few years.<\/p>\n<p>\u201cWe\u2019re not seeing one single strain of Shigella that\u2019s causing this emerging phenomenon. What we\u2019re seeing is the development of this resistance in a number of different strains that are occurring all over the country and in fact all over the world,\u201d Francois Watkins said.<\/p>\n<p>According to Francois Watkins, the increase in XDR cases indicates some selective pressure that is driving the Shigella bacteria to develop antibiotic resistance. She noted that a common driver in antibiotic resistance is the use of antibiotics not only in people but in animals and environmental settings.<\/p>\n<aside class=\"ad-unit ad-unit--mr2_ab\"><\/aside>\n<p>\u201cWe think that some of the best ways to combat this problem are to really have what we call judicious use, or conscientious use, of antibiotics in all of these different settings,\u201d said Francois Watkins.<\/p>\n<p>George Garcia, professor and chair of medicinal chemistry at the University of Michigan\u2019s College of Pharmacy, told The Hill that labs like his are looking into treatments that block a pathogen\u2019s ability to infect instead of targeting the pathogen itself. According to Garcia, these potential methods, targeting what are called \u201cvirulence factors,\u201d would places less pressure on bacteria to become antibiotic-resistant.<\/p>\n<p>Shigella is a close relative to the better-known E. coli bacteria and can similarly be spread through contaminated food and water, but is also spread through oral contact with feces. What sets Shigella apart from E. coli is its extremely high virulence, with as little as 10 microorganisms of the bacteria capable of causing an infection. <\/p>\n<aside class=\"ad-unit ad-unit--mr3_ab\"><\/aside>\n<p>In comparison, other common causes of gastrointestinal infections require hundreds or even thousands of bacterial organisms to cause illness.<\/p>\n<p>Symptoms of Shigella infections include diarrhea \u2014 which can be bloody \u2014 as well as fever and abdominal cramping. Most cases of the Shigella infection will resolve on their own without medical intervention.<\/p>\n<p>Garcia noted that blood in stool or diarrhea can be a telling indication for some that they have contracted Shigella.<\/p>\n<aside class=\"ad-unit ad-unit--mr4_ab\"><\/aside>\n<p>\u201cA lot of diarrheal diseases don\u2019t quite do that, but Shigella does,\u201d said Garcia. \u201cIt\u2019s not unique to Shigella but it would certainly be a red flag to me.\u201d<\/p>\n<p>The CDC noted in its health alert that it has observed an increase in Shigella cases among men who have sex with men, which Garcia attributed to the bacteria accumulating in the intestines and the prevalence and anal intercourse among this demographic.<\/p>\n<p>Francois Watkins said Shigella\u2019s potential as a sexually transmitted disease has been under recognized in the medical community.<\/p>\n<aside class=\"ad-unit ad-unit--mr5_ab\"><\/aside>\n<p>\u201cWe think that often its reputation within the medical community is more of a foodborne and person-to-person transmission mode that occurs like among young kids at daycares and things like that,\u201d Francois Watkins said. \u201cSo we think that it is under recognized as a sexually transmitted disease, but in the medical literature it\u2019s been known for many years that this is a possibility.\u201d<\/p>\n<\/div>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">News<\/a> articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/news\/\" target=\"_blank\" rel=\"noopener\">News category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/thehill.com\/policy\/healthcare\/3882518-why-concerns-are-rising-about-drug-resistant-shigella-infections\/\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Why concerns are rising about drug-resistant Shigella infections The health community is growing more concerned about Shigella bacteria infections that have shown a resistance to drugs. The Centers for Disease Control and Prevention (CDC) last week issued a health alert for a rise in infections caused by a drug-resistant strain of Shigella, bringing new attention&#8230;<\/p>\n","protected":false},"author":1,"featured_media":559425,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/thehill.com\/wp-content\/uploads\/sites\/2\/2023\/03\/health-wellness-avoid-drug-resistant-shigella-bacteria-tips.jpg?w=1280","fifu_image_alt":"","footnotes":""},"categories":[70897],"tags":[140907,134417,134343,71464,139529,134661,80445,71525,140908,134345],"class_list":["post-559424","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-bacterial-infection","tag-blog-briefing-room","tag-campaign","tag-cdc","tag-defense-national-security","tag-energy-environment","tag-healthcare","tag-national-security","tag-shigella","tag-state-watch"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/559424","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=559424"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/559424\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/559425"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=559424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=559424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=559424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}