{"id":563156,"date":"2023-03-13T20:56:40","date_gmt":"2023-03-13T17:56:40","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/cationic-conjugated-polymer-technique-can-identify-hypertension-risk-alleles\/"},"modified":"2023-03-13T20:56:40","modified_gmt":"2023-03-13T17:56:40","slug":"cationic-conjugated-polymer-technique-can-identify-hypertension-risk-alleles","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/cationic-conjugated-polymer-technique-can-identify-hypertension-risk-alleles\/","title":{"rendered":"#Cationic conjugated polymer technique can identify hypertension risk alleles"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a25996b31ad0\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a25996b31ad0\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/cationic-conjugated-polymer-technique-can-identify-hypertension-risk-alleles\/#%E2%80%9CCationic_conjugated_polymer_technique_can_identify_hypertension_risk_alleles%E2%80%9D\" >&#8220;Cationic conjugated polymer technique can identify hypertension risk alleles&#8221;<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E2%80%9CCationic_conjugated_polymer_technique_can_identify_hypertension_risk_alleles%E2%80%9D\"><\/span>&#8220;Cationic conjugated polymer technique can identify hypertension risk alleles&#8221;<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2023\/cationic-conjugated-po.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/2023\/cationic-conjugated-po.jpg\" data-sub-html=\"\">\n<figure class=\"article-img\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2023\/cationic-conjugated-po.jpg\" alt=\"Cationic conjugated polymer technique can identify HTN risk alleles\" width=\"800\" height=\"530\"\/><\/figure>\n<\/div>\n<\/div>\n<p>A cationic conjugated polymer (CCP)-based multistep fluorescence resonance energy transfer (MS-FRET) technique, which identifies hypertensive risk alleles, can improve and shorten the time to blood pressure control, according to a study published in the March 8 issue of <i><a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">Science<\/a> Translational Medicine<\/i>.<\/p>\n<p>Qi Shen, from the Beijing National Laboratory for Molecular Sciences at the Chinese Academy of Sciences, and colleagues used a CCP-based MS-FRET technique to qualitatively analyze DNA genotypes associated with hypertension.<\/p>\n<p>The researchers found that in a retrospective study of whole-blood samples from 150 patients hospitalized with hypertension, this technique successfully identified known hypertensive risk alleles on assessment of 10 genetic loci.<\/p>\n<p>The detection method was then <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>lied to a prospective clinical trial of 100 patients with essential hypertension. Based on the results from the MS-FRET technique, personalized treatment of patients with hypertension could effectively improve the rate of blood pressure control (94.0 versus 54.0 percent) and shorten the time to blood pressure control relative to conventional treatment (4.06 versus 5.82 days).<\/p>\n<p>&#8220;Our system has the advantages of simple operation and high throughput detection, providing a potentially useful tool to aid in management of hypertension,&#8221; the authors write. &#8220;This system could be applied to maximize the efficacy of antihypertensive medication and reduce rates of uncontrolled hypertension, particularly in resource-limited settings.&#8221;<\/p>\n<p>Several authors are inventors on a Chinese patent application.<\/p>\n<div class=\"article-main__more p-4\">\n                                                                                                    <strong>More information:<\/strong><br \/>\n                                                    Qi Shen et al, Sensitive detection of single-nucleotide polymorphisms by conjugated polymers for personalized treatment of hypertension, <i>Science Translational Medicine<\/i> (2023).  <a rel=\"nofollow noopener\" target=\"_blank\" data-doi=\"1\" href=\"https:\/\/dx.doi.org\/10.1126\/scitranslmed.abq5753\">DOI: 10.1126\/scitranslmed.abq5753<\/a><\/p><\/div>\n<p class=\"article-main__note mt-4\">\n                                                Copyright \u00a9 2023 <a rel=\"nofollow noopener\" target=\"_blank\" href=\"http:\/\/www.healthday.com\/\">HealthDay<\/a>. All rights reserved.<\/p>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Cationic conjugated polymer technique can identify hypertension risk alleles (2023, March 13)<br \/>\n                                                 retrieved 13 March 2023<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2023-03-cationic-conjugated-polymer-technique-hypertension.html<\/p>\n<p>                                            This document is subject to copyright. 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Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Like this articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/science\/\" target=\"_blank\" rel=\"noopener\">Science category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/medicalxpress.com\/news\/2023-03-cationic-conjugated-polymer-technique-hypertension.html\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Cationic conjugated polymer technique can identify hypertension risk alleles&#8221; A cationic conjugated polymer (CCP)-based multistep fluorescence resonance energy transfer (MS-FRET) technique, which identifies hypertensive risk alleles, can improve and shorten the time to blood pressure control, according to a study published in the March 8 issue of Science Translational Medicine. 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