{"id":593360,"date":"2023-10-05T17:54:43","date_gmt":"2023-10-05T14:54:43","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/3d-printed-stem-cells-could-help-treat-brain-injuries\/"},"modified":"2023-10-05T17:54:43","modified_gmt":"2023-10-05T14:54:43","slug":"3d-printed-stem-cells-could-help-treat-brain-injuries","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/3d-printed-stem-cells-could-help-treat-brain-injuries\/","title":{"rendered":"#3D-printed stem cells could help treat brain injuries"},"content":{"rendered":"<div id=\"article-main-content\">\n                            In a scientific first, researchers at theUniversity of Oxford have 3D printed stem cells that can mimic the architecture of the cerebral cortex, the human brain\u2019s outer layer. The technique could potentially be used to treat brain injuries.<\/p>\n<p>Such injuries typically cause significant damage to the cerebral cortex, leading to movement, cognition, and communication challenges. Currently, there\u2019s no effective treatment for severe cases, which negatively impacts the patients\u2019 quality of life.<\/p>\n<p>Hoping to change this, the research team fabricated a two-layered brain tissue by 3D printing human neural stem cells.<\/p>\n<p>To achieve this, the researchers used human induced pluripotent stem cells (hiPSCs), which can be easily derived from cells harvested from the patients themselves, reducing the risk of an immune response.<\/p>\n<p>Initially, the hiPSCs were differentiated into neural progenitor cells for two separate layers of the cerebral cortex. They were then suspended in a solution to produce two \u201cbioinks,\u201d which were printed to create a two-layered structure of brain tissue.<\/p>\n<div class=\"inarticle-wrapper latest channel-cta hs-embed-tnw\">\n<div id=\"hs-embed-tnw\" class=\"channel-cta-wrapper\">\n<div class=\"channel-cta-img\"><img decoding=\"async\" class=\"js-lazy\" src=\"https:\/\/s3.amazonaws.com\/events.tnw\/hardfork-2018\/uploads\/visuals\/tnw-newsletter.png\"\/><\/div>\n<p><noscript><img decoding=\"async\" src=\"https:\/\/s3.amazonaws.com\/events.tnw\/hardfork-2018\/uploads\/visuals\/tnw-newsletter.png\"\/><\/noscript><\/p>\n<div class=\"channel-cta-input\">\n<p class=\"channel-cta-title\">The &lt;3 of EU tech<\/p>\n<p class=\"channel-cta-tagline\">The latest rumblings from the EU tech scene, a story from our wise ol&#8217; founder Boris, and some questionable AI art. It&#8217;s free, every week, in your inbox. Sign up now!<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>Notably, when implanted into mouse brains, the printed cells showed both structural and functional integration with the host tissue.<\/p>\n<figure class=\"post-image post-mediaBleed aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-1400454 js-lazy\" alt=\"stem cell brain implant in mice \" width=\"1640\" height=\"886\" sizes=\"auto, (max-width: 1640px) 100vw, 1640px\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21.png\" srcset=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21.png 1640w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-280x151.png 280w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-250x135.png 250w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-500x270.png 500w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-1536x830.png 1536w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-796x430.png 796w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-1592x860.png 1592w\"\/><figcaption><a rel=\"nofollow noopener\" target=\"_blank\" href=\"#\" data-url=\"https:\/\/twitter.com\/intent\/tweet?url=https%3A%2F%2Feditorial.thenextweb.com%2Fdeep-tech%2F2023%2F10%2F05%2F3d-printed-stem-cells-help-treat-brain-injuries%2F&amp;via=thenextweb&amp;related=thenextweb&amp;text=Check out this picture on: Diagram of the process, from the differentiation of the stem cells to their implantation into mice. Credit: Yongcheng Jin\/ University of Oxford\" data-title=\"Share Diagram of the process, from the differentiation of the stem cells to their implantation into mice. Credit: Yongcheng Jin\/ University of Oxford on Twitter\" data-width=\"685\" data-height=\"500\" class=\"post-image-share popitup\" title=\"Share Diagram of the process, from the differentiation of the stem cells to their implantation into mice. Credit: Yongcheng Jin\/ University of Oxford on Twitter\"><i class=\"icon icon--inline icon--twitter--dark\"\/><\/a>Diagram of the process, from the differentiation of the stem cells to their implantation into mice. Credit: Yongcheng Jin\/ University of Oxford<\/figcaption><noscript><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-1400454\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21.png\" alt=\"stem cell brain implant in mice \" width=\"1640\" height=\"886\" srcset=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21.png 1640w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-280x151.png 280w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-250x135.png 250w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-500x270.png 500w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-1536x830.png 1536w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-796x430.png 796w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Screenshot-2023-10-05-at-15.55.21-1592x860.png 1592w\"\/><\/noscript><\/figure>\n<p>\u201cOur droplet printing technique provides a means to engineer living 3D tissues with desired architectures, which brings us closer to the creation of personalised implantation treatments for brain injury,\u201d <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.ox.ac.uk\/news\/2023-10-04-oxford-researchers-develop-3d-printing-method-shows-promise-repairing-brain-injuries\">said<\/a> Dr Linna Zhou, senior author of the study.<\/p>\n<p>The researchers now aim to further evolve their technique and create complex multi-layered cerebral cortex tissues that can mimic the human brain\u2019s architecture in a more realistic way. Beyond brain injuries, these 3D-printed cells could benefit drug evaluation and our knowledge on brain development and cognition.<\/p>\n<p>The full study is published in the journal <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41467-023-41356-w\">Nature Communications<\/a>.\n                        <\/div>\n<p><script async src=\"\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMLG0nwswvr63Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\">For forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong>\n<\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more like this article, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/technology\/\" target=\"_blank\" rel=\"noopener\">Technology category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/thenextweb.com\/news\/3d-printed-stem-cells-help-treat-brain-injuries\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a scientific first, researchers at theUniversity of Oxford have 3D printed stem cells that can mimic the architecture of the cerebral cortex, the human brain\u2019s outer layer. The technique could potentially be used to treat brain injuries. Such injuries typically cause significant damage to the cerebral cortex, leading to movement, cognition, and communication challenges&#8230;.<\/p>\n","protected":false},"author":1,"featured_media":593361,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/img-cdn.tnwcdn.com\/image\/tnw-blurple?filter_last=1&fit=1280,640&url=https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2023\/10\/Untitled-design-17-1.jpg&signature=669137c2d27d3aab8c9eb4ff9d9ba67d","fifu_image_alt":"","footnotes":""},"categories":[18],"tags":[],"class_list":["post-593360","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/593360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=593360"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/593360\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/593361"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=593360"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=593360"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=593360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}