{"id":60431,"date":"2020-09-04T18:49:00","date_gmt":"2020-09-04T15:49:00","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/panel-says-its-still-too-soon-to-try-altering-human-embryo-dna\/"},"modified":"2020-09-04T18:49:00","modified_gmt":"2020-09-04T15:49:00","slug":"panel-says-its-still-too-soon-to-try-altering-human-embryo-dna","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/panel-says-its-still-too-soon-to-try-altering-human-embryo-dna\/","title":{"rendered":"#Panel says its still too soon to try altering human embryo DNA"},"content":{"rendered":"<p>&#8220;<strong>#Panel says its still too soon to try altering human embryo DNA<\/strong>&#8221;<\/p>\n<div id=\"article-wrapper\" role=\"main\">\n<div>\n<div>\n<p>        September 4, 2020 <span>|<\/span> 11:49am            <\/p>\n<div id=\"featured-image-wrapper\">\n                        Enlarge Image<\/p>\n<p><img decoding=\"async\" alt=\"Chinese scientists load Cas9 protein and PCSK9 sgRNA molecules into a fine glass pipette at a laboratory in Shenzhen in southern China's Guangdong province.\" id=\"standard-article-image\"  src=\"https:\/\/nypost.com\/wp-content\/uploads\/sites\/2\/2020\/09\/embroyo-dna-01.jpg?quality=90&#038;strip=all&#038;w=618&#038;h=410&#038;crop=1\" ><\/img><br \/>\n                <span>Chinese scientists load Cas9 protein and PCSK9 sgRNA molecules into a fine glass pipette at a laboratory in Shenzhen in southern China&#8217;s Guangdong province.<\/span><br \/>\n                            <span>AP<\/span><\/p><\/div>\n<div>\n                        It\u2019s still too soon to try to make genetically edited babies because the <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/sciencee\/\" data-internallinksmanager029f6b8e52c=\"5\" title=\"Science\" target=\"_blank\" rel=\"noopener\">science<\/a> isn\u2019t advanced enough to ensure safety, says an international panel of experts who also m<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ed a pathway for any countries that want to consider it.<\/p>\n<p>Thursday\u2019s report comes nearly two years after a Chinese scientist shocked the world by revealing he\u2019d helped make the first gene-edited babies using a tool called CRISPR, which enables DNA changes or \u201cedits\u201d that can pass to future generations. He Jianqui did this to three babies when they were embryos to try to make them resistant to infection with the AIDS virus and described it in exclusive interviews with The Associated Press.<\/p>\n<p>Mainstream scientists condemned his experiment as unethical and He was sentenced to three years in prison for violating Chinese laws. The experts commission was formed in the aftermath by the US National Academy of Medicine, US National Academy of Sciences and the United Kingdom\u2019s Royal Society.<\/p>\n<p>The group doesn\u2019t take a stance on whether editing embryos is ethical, just whether it\u2019s ready scientifically \u2014 and deems that it\u2019s not. A separate panel formed by the World Health Organization is to report on ethics issues later this year.<\/p>\n<p>The commission does say that if a country allows this, it should be limited to cases where people have no or very poor options for having a child without the disease. Initial attempts should be for serious diseases caused by a single gene, such as muscular dystrophy, cystic fibrosis, the blood disorder beta thalassemia and Tay-Sachs, a neurological disease, the report says.<\/p>\n<p>Altering genes to try to enhance traits such as muscle mass or height is not endorsed.<\/p>\n<p>It gives \u201cmuch better clarity about what it would take to go forward and that now is not the time,\u201d said Jeffrey Kahn, bioethics chief at Johns Hopkins University and a member of the panel.<\/p>\n<figure id=\"attachment_16246410\"><img alt=\"He Jiankui.\" data- data- height=\"441\" width=\"662\"><\/img><figcaption><span>He Jiankui.<\/span><span>AP<\/span><\/figcaption><\/figure>\n<p>Whether editing is acceptable from an ethics and societal perspective \u201cneeds to be answered country by country,\u201d he said. \u201cYou\u2019re modifying a future human. It\u2019s a big step.\u201d<\/p>\n<p>The panel recommended that:<\/p>\n<ul>\n<li>Pregnancy with edited embryos should not be attempted unless it\u2019s clearly possible to make only the intended gene changes and not any unintended ones, which can\u2019t be done now.<\/li>\n<li>Extensive public discussions should be held before any country decides to allow editing embryos, eggs or sperm. A regulatory system needs to be in place to ensure oversight and publication of results and to prevent bias or discrimination.<\/li>\n<li>Initial uses should be limited to cases meeting four criteria: a serious disease caused by a single gene; editing is limited to changing a problem DNA sequence to one that is known to be safe in the <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/general\/\" data-internallinksmanager029f6b8e52c=\"3\" title=\"General\" target=\"_blank\" rel=\"noopener\">general<\/a> population; no embryos without the problem gene are edited and parents lack a good way to have a child without the disease because of fertility problems or other issues.<\/li>\n<li>Edited embryos should be studied in the lab to ensure they\u2019re developing normally and tests should be done to verify that all cells were altered as intended before they\u2019re used to attempt pregnancy.<\/li>\n<li>An international scientific advisory panel should be formed to give regular updates on science advances, assess if requirements have been met for embryo editing, review results from any cases and help any countries seeking advice.<\/li>\n<\/ul>\n<p>\u201cOur group was very concerned about the potential for rogue scientists\u201d to proceed on their own and included advice that there needs to be a way for whistleblowers to report unethical work, said Richard Lifton, president of the Rockefeller University in New York and co-leader of the panel.<\/p>\n<p>Some scientists not connected with the work expressed surprise at the panel\u2019s inclusion of diseases such as sickle cell and cystic fibrosis, which have a wide range of severity and existing treatments.<\/p>\n<p>If drugs or gene therapy after birth can treat a disease, \u201cthen it doesn\u2019t make sense to me to layer the additional medical and ethical risks\u201d of editing embryos to try to prevent it, said David Liu, Harvard University professor and co-founder of several gene-editing companies. He is paid by the Howard Hughes Medical Institute, which also supports AP\u2019s Health &#038; Science Department.<\/p>\n<p>Jennifer Doudna, a gene-editing pioneer from the University of California, Berkeley, said she also was struck by the inclusion of cystic fibrosis.<\/p>\n<p>\u201cIt\u2019s a disease that can be managed in some cases,\u201d she said.<\/p>\n<p>Gene editing of blood cells after birth seems a potential cure for sickle cell and \u201cthere\u2019s already been success with one patient\u201d using CRISPR, she noted.<\/p>\n<p>Kahn said not every case would meet all of the criteria the panel set and if gene therapy turns out to work, \u201cI think we have a different conversation\u201d about editing\u2019s risks and benefits.<\/p>\n<p>Regardless, the report shows that editing embryos, eggs or sperm should not be done yet because \u201cthe <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/technology\/\" data-internallinksmanager029f6b8e52c=\"4\" title=\"Technology\" target=\"_blank\" rel=\"noopener\">technology<\/a> is too early stage,\u201d Doudna said.<\/p>\n<p>\u201cIf there ever was confusion or if anyone in the past could say it wasn\u2019t clear \u2026 it\u2019s now very clear\u201d that it\u2019s taboo, she said. Gene editing is a powerful technology and should be pursued with international standards and full transparency, \u201cnot having it happening in the shadows.\u201d\n            <\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Technology <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">News<\/a> articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/technology\/\" target=\"_blank\" rel=\"noopener noreferrer\">Technology category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>if you want to <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/watch-movies-tv-seriess\/\" data-internallinksmanager029f6b8e52c=\"8\" title=\"Watch Movies &amp; TV Series\" target=\"_blank\" rel=\"noopener\">watch Movies<\/a> or Tv Shows go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/dizi.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">Dizi.BuradaBiliyorum.Com<\/a> <\/span> for forums sites go to <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/forum.buradabiliyorum.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">Forum.BuradaBiliyorum.Com<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/nypost.com\/2020\/09\/04\/still-too-soon-to-try-altering-human-embryo-dna-panel-says\/\" target=\"_blank\" rel=\"noopener noreferrer\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;#Panel says its still too soon to try altering human embryo DNA&#8221; September 4, 2020 | 11:49am Enlarge Image Chinese scientists load Cas9 protein and PCSK9 sgRNA molecules into a fine glass pipette at a laboratory in Shenzhen in southern China&#8217;s Guangdong province. AP It\u2019s still too soon to try to make genetically edited babies&#8230;<\/p>\n","protected":false},"author":1,"featured_media":60432,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[18],"tags":[64624],"class_list":["post-60431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology","tag-panel-says-its-still-too-soon-to-try-altering-human-embryo-dna"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/60431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=60431"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/60431\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/60432"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=60431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=60431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=60431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}