{"id":609968,"date":"2024-02-23T20:43:16","date_gmt":"2024-02-23T17:43:16","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/this-startup-is-bioengineering-tissue-into-human-vein-implants\/"},"modified":"2024-02-23T20:43:16","modified_gmt":"2024-02-23T17:43:16","slug":"this-startup-is-bioengineering-tissue-into-human-vein-implants","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/this-startup-is-bioengineering-tissue-into-human-vein-implants\/","title":{"rendered":"#This startup is bioengineering tissue into human vein implants"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a2432bf5c10d\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a2432bf5c10d\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/this-startup-is-bioengineering-tissue-into-human-vein-implants\/#Bioengineering_body_parts\" >Bioengineering body parts<\/a><\/li><\/ul><\/nav><\/div>\n<div id=\"article-main-content\">\n                            Norwegian startup ClexBio is bioengineering human veins to implant inside a patient\u2019s body.<\/p>\n<p>Together with CSEM, a Swiss R&amp;D centre, the company has built a prototype bioreactor to grow the veins.<\/p>\n<p>Pre-clinical tests in animal models are already underway. Based on the early results, the team is confident that the implants don\u2019t trigger an immune response in patients. Instead, they turn into functional tissue that integrates with the body.<\/p>\n<p>If further tests prove successful, the implants could treat\u00a0severe chronic venous insufficiency, a painful condition caused when veins have problems moving blood to the heart.<\/p>\n<div class=\"inarticle-wrapper latest channel-cta hs-embed-tnw\">\n<div id=\"hs-embed-tnw\" class=\"channel-cta-wrapper\">\n<div class=\"channel-cta-img\"><img decoding=\"async\" class=\"js-lazy\" src=\"https:\/\/s3.amazonaws.com\/events.tnw\/hardfork-2018\/uploads\/visuals\/tnw-newsletter.png\"\/><\/div>\n<p><noscript><img decoding=\"async\" src=\"https:\/\/s3.amazonaws.com\/events.tnw\/hardfork-2018\/uploads\/visuals\/tnw-newsletter.png\"\/><\/noscript><\/p>\n<div class=\"channel-cta-input\">\n<p class=\"channel-cta-title\">The &lt;3 of EU tech<\/p>\n<p class=\"channel-cta-tagline\">The latest rumblings from the EU tech scene, a story from our wise ol&#8217; founder Boris, and some questionable AI art. It&#8217;s free, every week, in your inbox. Sign up now!<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>But veins are just the start of the company\u2019s ambitions. <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.clexbio.com\/\">ClexBio<\/a> envisions bioengineering producing various medical treatments.<\/p>\n<p>\u201cIn the future, we believe tissue therapeutic solutions will provide a cure for many of the chronic conditions that are debilitating for our society today,\u201d Armend H\u00e5ti, the startup\u2019s CEO and co-founder, told TNW.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Bioengineering_body_parts\"><\/span>Bioengineering body parts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<figure class=\"post-image post-mediaBleed aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-1404222 js-lazy\" alt=\"A series of bioreactors for bioengineering vein grafts, developed by CSEM and ClexBio\" width=\"1640\" height=\"1093\" sizes=\"auto, (max-width: 1640px) 100vw, 1640px\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1.jpg\" srcset=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1.jpg 1640w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-280x187.jpg 280w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-203x135.jpg 203w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-405x270.jpg 405w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-1536x1024.jpg 1536w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-796x531.jpg 796w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-1592x1061.jpg 1592w\"\/><figcaption><a rel=\"nofollow noopener\" target=\"_blank\" href=\"#\" data-url=\"https:\/\/twitter.com\/intent\/tweet?url=https%3A%2F%2Feditorial.thenextweb.com%2Fdeep-tech%2F2024%2F02%2F23%2Fclexbio-bioengineers-human-veins%2F&amp;via=thenextweb&amp;related=thenextweb&amp;text=Check out this picture on: The new tech aims to scale bioengineering. Credit: ClexBio\" data-title=\"Share The new tech aims to scale bioengineering. Credit: ClexBio on Twitter\" data-width=\"685\" data-height=\"500\" class=\"post-image-share popitup\" title=\"Share The new tech aims to scale bioengineering. Credit: ClexBio on Twitter\"><i class=\"icon icon--inline icon--twitter--dark\"\/><\/a>The new tech aims to scale bioengineering. Credit: ClexBio<\/figcaption><noscript><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-1404222\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1.jpg\" alt=\"A series of bioreactors for bioengineering vein grafts, developed by CSEM and ClexBio\" width=\"1640\" height=\"1093\" srcset=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1.jpg 1640w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-280x187.jpg 280w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-203x135.jpg 203w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-405x270.jpg 405w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-1536x1024.jpg 1536w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-796x531.jpg 796w, https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/unnamed-1-1592x1061.jpg 1592w\"\/><\/noscript><\/figure>\n<p><span style=\"font-weight: 400;\">At the core of ClexBio\u2019s tech is the VivoSet platform, which can cultivate tissues into real human anatomies, such as veins. <\/span><\/p>\n<p>To produce them in a scalable fashion, the startup developed the bioreactor.<\/p>\n<p>Inside the machine, <span>the veins mature over a few weeks in a sterile environment. Automated <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/social-mediaa\/\" data-internallinksmanager029f6b8e52c=\"1\" title=\"Social Media\" target=\"_blank\" rel=\"noopener\">media<\/a> circulation provides the tissue with oxygen and nutrients.<\/span><\/p>\n<p><span>\u201cUsing a closed system to generate the vein grafts reduces the risk of contamination, ensures product quality and safety, and facilitates regulatory compliance,\u201d H\u00e5ti said. <\/span><\/p>\n<p><span>\u201cThis is a vital prerequisite for our ability to conduct in-human studies and scale up commercially in a GMP [Good Manufacturing Practices]\u00a0setting in the future.\u201d<\/span><span>\u00a0<\/span><\/p>\n<p>As the veins mature, the system forms them into a graft. ClexBio said they can then be implanted into patients \u201coff the shelf.\u201d<\/p>\n<p>Before that h<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ens, the tech will have to pass an array of tests and clear regulatory reviews. But <span>H\u00e5ti<\/span> is already imagining the real-world impact.<\/p>\n<p><span>\u201cWe are truly excited about the paradigm shift this may usher in for human surgery and the treatment of damaged tissues,\u201d he said. <\/span><\/p>\n<p><span>\u201cWe are moving away from a world of synthetic implants and stepping into the world of bioengineering.\u201d<\/span>\n                        <\/div>\n<p><script async src=\"\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMN63nwsw68G3Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more like this article, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/technology\/\" target=\"_blank\" rel=\"noopener\">Technology category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/thenextweb.com\/news\/clexbio-bioengineers-human-veins\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Norwegian startup ClexBio is bioengineering human veins to implant inside a patient\u2019s body. Together with CSEM, a Swiss R&amp;D centre, the company has built a prototype bioreactor to grow the veins. Pre-clinical tests in animal models are already underway. Based on the early results, the team is confident that the implants don\u2019t trigger an immune&#8230;<\/p>\n","protected":false},"author":1,"featured_media":609969,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/img-cdn.tnwcdn.com\/image\/tnw-blurple?filter_last=1&fit=1280,640&url=https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2024\/02\/Untitled-design-1-6.jpg&signature=36894271dd7e302a2d7913b8fd573de7","fifu_image_alt":"","footnotes":""},"categories":[18],"tags":[],"class_list":["post-609968","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/609968","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=609968"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/609968\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/609969"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=609968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=609968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=609968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}