{"id":613152,"date":"2024-03-17T19:10:01","date_gmt":"2024-03-17T16:10:01","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research\/"},"modified":"2024-03-17T19:10:01","modified_gmt":"2024-03-17T16:10:01","slug":"pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research\/","title":{"rendered":"#Pacemaker powered by light eliminates need for batteries and allows the heart to function more naturally\u2014new research"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6af68727c9d52\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6af68727c9d52\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research\/#Why_it_matters\" >Why it matters<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/buradabiliyorum.com\/en\/pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research\/#Whats_next\" >What&#8217;s next<\/a><\/li><\/ul><\/nav><\/div>\n<div>\n<p>By harnessing light, my colleagues <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/scholar.google.com.sg\/citations?user=hO6bRlwAAAAJ&amp;hl=en\">and I<\/a> designed a wireless, ultrathin pacemaker that operates like a solar panel. This design not only eliminates the need for batteries but also minimizes disruptions to the heart&#8217;s natural function by molding to its contours. Our research, recently <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/doi.org\/10.1038\/s41586-024-07016-9\">published in the journal <i>Nature<\/i><\/a>, offers a new <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>roach to treatments that require electrical stimulation, such as heart pacing.<\/p>\n<p>Pacemakers are medical devices implanted in the body to regulate heart rhythms. They&#8217;re composed of electronic circuits with batteries and leads anchored to the heart muscle to stimulate it. However, leads can fail and damage tissue. The location of the leads can&#8217;t be changed once they&#8217;re implanted, limiting access to different heart regions. Because pacemakers use rigid, metallic electrodes, they may also damage tissue when <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nhlbi.nih.gov\/health\/heart-surgery\/during\">restarting the heart after surgery<\/a> or <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/heart-arrhythmia\/symptoms-causes\/syc-20350668\">regulating arrhythmia<\/a>.<\/p>\n<p>Our team envisioned a leadless and more flexible pacemaker that could precisely stimulate multiple areas of the heart. So we designed a device that <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/doi.org\/10.1038\/s41586-024-07016-9\">transforms light into bioelectricity<\/a>, or heart cell-generated electrical signals. Thinner than a human hair, our pacemaker is made of an optic fiber and silicon membrane that the <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/tianlab.uchicago.edu\/\">Tian lab<\/a> and colleagues at the University of Chicago <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/pme.uchicago.edu\/\">Pritzker School of Molecular Engineering<\/a> have spent years developing.<\/p>\n<p>Unlike <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.energy.gov\/eere\/solar\/solar-photovoltaic-cell-basics\">conventional solar cells<\/a> that are usually designed to collect as much energy as possible, we tweaked our device to generate electricity only at points where light strikes so it can precisely regulate heartbeats. We did this by using a layer of very small pores that can trap light and electrical current. Only cardiac muscles exposed to light-activated pores are stimulated.<\/p>\n<p>Because our device is so small and light, it can be implanted without opening the chest. We were able to <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/doi.org\/10.1038\/s41586-024-07016-9\">successfully implant it<\/a> in the hearts of rodents and an adult pig, pacing the beats of different heart muscles. Because pig hearts are anatomically similar to human hearts, this accomplishment shows our device&#8217;s potential to translate to people.<\/p>\n<p>                                                                                                        <!-- Google middle Adsense block --><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_it_matters\"><\/span>Why it matters<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Heart disease is the <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/the-top-10-causes-of-death\">leading cause of death around the world<\/a>. Annually, <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nhlbi.nih.gov\/health\/heart-surgery\">over 2 million people<\/a> undergo open-heart surgery to treat heart problems, including to implant devices that regulate heart rhythms and prevent heart attacks.<\/p>\n<p>Our ultralight device gently conforms to the surface of the heart, enabling less invasive stimulation and improved pacing and synchronized contraction. To reduce postoperative trauma and recovery time, our device can be implanted with a minimally invasive technique.<\/p>\n<figure class=\"mb-4\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/VideoObject\"><meta itemprop=\"name\" content=\"Pacemaker powered by light eliminates need for batteries and allows the heart to function more naturally \u2212 new research\"\/><meta itemprop=\"url\" content=\"https:\/\/www.youtube.com\/watch\/?v=KG_M7iD90CQ\"\/><meta itemprop=\"description\" content=\"Like solar panels, this pacemaker is powered by light.\"\/><meta itemprop=\"uploadDate\" content=\"2024-03-15T09:42:09-04:00\"\/><meta itemprop=\"embedUrl\" content=\"https:\/\/www.youtube.com\/embed\/KG_M7iD90CQ\"\/><meta itemprop=\"thumbnailUrl\" content=\"https:\/\/img.youtube.com\/vi\/KG_M7iD90CQ\/maxresdefault.jpg\"\/><br \/>\n             <iframe loading=\"lazy\" title=\"New pacemaker design powers the heart with light\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/KG_M7iD90CQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><figcaption class=\"text-darken text-low-up mt-4\" itemprop=\"caption\">Like solar panels, this pacemaker is powered by light.<\/figcaption><\/figure>\n<p> <b>What still isn&#8217;t known<\/b><\/p>\n<p>Currently, our <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/technology\/\" data-internallinksmanager029f6b8e52c=\"4\" title=\"Technology\" target=\"_blank\" rel=\"noopener\">technology<\/a> is best first used for urgent heart conditions, including restarting the heart after surgery, heart attack and ventricular defibrillation. We continue to explore its long-term effects and durability in the human body.<\/p>\n<p>The body&#8217;s internal environment is <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/doi.org\/10.1017\/jfm.2022.272\">rich in fluids<\/a> that are disturbed by the heart&#8217;s constant mechanical motion. This could potentially compromise the device&#8217;s functionality over time.<\/p>\n<p>Moreover, researchers don&#8217;t fully understand how the body reacts to prolonged exposure to medical devices. The formation of scar tissue around the device after implantation can diminish its sensitivity. We are developing special surface treatments and biomaterial coatings to decrease the likelihood of rejection.<\/p>\n<p>Although the breakdown of our device results in a nontoxic substance the body can safely absorb called <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/doi.org\/10.1038\/s41578-020-0230-0\">silicic acid<\/a>, evaluating how the body responds to extended implantation is essential to ensure safety and effectiveness.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Whats_next\"><\/span>What&#8217;s next<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>To achieve long-term implantation and tailor the device to each patient, we are refining the rate at which it dissolves naturally in the body. We are exploring enhancements to make the device compatible as a wearable pacemaker. This involves integrating a wireless light-emitting diode, or LED, beneath the skin that is connected to the device via an optical fiber.<\/p>\n<p>Our ultimate goal is to broaden the scope of what we call photoelectroceuticals beyond cardiac care. This includes neurostimulation, neuroprostheses and pain management to treat neurodegenerative conditions such as <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.parkinson.org\/understanding-parkinsons\/statistics\">Parkinson&#8217;s disease<\/a>.<\/p>\n<div class=\"d-inline-block text-medium my-4\">\n                                                Provided by<br \/>\n                                                                                                    The Conversation<br \/>\n                                                                                                        <a rel=\"nofollow noopener\" target=\"_blank\" class=\"icon_open\" href=\"https:\/\/theconversation.com\"><br \/>\n                                                        <svg><use href=\"https:\/\/medx.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/><\/svg><\/a><\/p><\/div>\n<p>                                                                                                                            This article is republished from <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/theconversation.com\">The Conversation<\/a> under a Creative Commons license. Read the <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/theconversation.com\/pacemaker-powered-by-light-eliminates-need-for-batteries-and-allows-the-heart-to-function-more-naturally-new-research-224350\">original article<\/a>.<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/counter.theconversation.com\/content\/224350\/count.gif?distributor=republish-lightbox-advanced\" alt=\"The Conversation\" width=\"1\" height=\"1\"\/><\/p>\n<p>                                        <!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>                                                 <strong>Citation<\/strong>:<br \/>\n                                                 Pacemaker powered by light eliminates need for batteries and allows the heart to function more naturally\u2014new research (2024, March 17)<br \/>\n                                                 retrieved 17 March 2024<br \/>\n                                                 from https:\/\/medicalxpress.com\/<a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>\/2024-03-pacemaker-powered-batteries-heart-function.html<\/p>\n<p>                                            This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no<br \/>\n                                            part may be reproduced without the written permission. The content is provided for information purposes only.<\/p><\/div>\n<\/p><\/div>\n<p><script id=\"facebook-jssdk\" async=\"\" src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMN63nwsw68G3Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Like this articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/science\/\" target=\"_blank\" rel=\"noopener\">Science category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/medicalxpress.com\/news\/2024-03-pacemaker-powered-batteries-heart-function.html\" target=\"_blank\" rel=\"noopener\">Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>By harnessing light, my colleagues and I designed a wireless, ultrathin pacemaker that operates like a solar panel. This design not only eliminates the need for batteries but also minimizes disruptions to the heart&#8217;s natural function by molding to its contours. Our research, recently published in the journal Nature, offers a new approach to treatments&#8230;<\/p>\n","protected":false},"author":1,"featured_media":613153,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/2024\/pacemaker-powered-by-l.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-613152","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/613152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=613152"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/613152\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/613153"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=613152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=613152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=613152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}