{"id":643352,"date":"2024-11-04T21:40:02","date_gmt":"2024-11-04T18:40:02","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/transcatheter-valve-replacement-best-for-severe-tricuspid-regurgitation\/"},"modified":"2024-11-04T21:40:02","modified_gmt":"2024-11-04T18:40:02","slug":"transcatheter-valve-replacement-best-for-severe-tricuspid-regurgitation","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/transcatheter-valve-replacement-best-for-severe-tricuspid-regurgitation\/","title":{"rendered":"#Transcatheter valve replacement best for severe tricuspid regurgitation"},"content":{"rendered":"
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Transcatheter tricuspid-valve replacement is superior to medical therapy alone for patients with severe tricuspid regurgitation, according to a study published<\/a> online Oct. 30 in the New England Journal of Medicine<\/i> to coincide with the annual Transcatheter Cardiovascular Therapeutics conference<\/a>, held from Oct. 27 to 30 in Washington, D.C.<\/p>\n

Rebecca T. Hahn, M.D., from the Columbia University Irving Medical Center in New York City, and colleagues randomly assigned 400 patients with severe symptomatic tricuspid regurgitation to undergo transcatheter tricuspid-valve replacement and medical therapy (valve-replacement group) or medical therapy alone (control group; 267 and 133 patients, respectively). All possible patient pairs were compared to calculate the win ratio for the primary outcome.<\/p>\n

The researchers found that the win ratio favoring valve replacement was 2.02 at one year. More wins occurred among patients in the valve-replacement group versus the control group with respect to death from any cause (14.8 versus 12.5%), postindex tricuspid-valve intervention (3.2 versus 0.6%), and improvement in the Kansas City Cardiomyopathy Questionnaire overall summary score (23.1 versus 6.0%), New York Heart Association functional class (10.2 versus 0.8%), and six-minute walk distance (1.1 versus 0.9%).<\/p>\n

With respect to the annualized rate of hospitalization for heart failure, the valve-replacement group had fewer wins than the control group (9.7 versus 10.0%). Severe bleeding occurred in 15.4 and 5.3% of the valve-replacement and control groups, respectively.<\/p>\n

“In patients with severe tricuspid regurgitation, transcatheter tricuspid-valve replacement plus medical therapy was superior to medical therapy alone,” the authors write.<\/p>\n

The study was funded by Edwards Lifescience<\/a>s.<\/p>\n

\n More information:<\/strong>
\n Rebecca T. Hahn et al, Transcatheter Valve Replacement in Severe Tricuspid Regurgitation, New England Journal of Medicine<\/i> (2024). DOI: 10.1056\/NEJMoa2401918<\/a><\/p>\n

Patrick T. O’Gara, Early-Stage Results with Transcatheter Tricuspid-Valve Replacement, New England Journal of Medicine<\/i> (2024). DOI: 10.1056\/NEJMe2413200<\/a><\/p><\/div>\n

\n \u00a9 2024 HealthDay<\/a>. All rights reserved.\n <\/p>\n

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Citation<\/strong>:
\n Transcatheter valve replacement best for severe tricuspid regurgitation (2024, November 4)
\n retrieved 4 November 2024
\n from https:\/\/medicalxpress.com\/news<\/a>\/2024-11-transcatheter-valve-severe-tricuspid-regurgitation.html<\/p>\n

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