{"id":663467,"date":"2025-04-18T05:25:13","date_gmt":"2025-04-18T02:25:13","guid":{"rendered":"https:\/\/en.buradabiliyorum.com\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/"},"modified":"2025-04-18T05:25:13","modified_gmt":"2025-04-18T02:25:13","slug":"why-its-important-for-cells-to-make-copies-on-an-exacting-schedule","status":"publish","type":"post","link":"https:\/\/buradabiliyorum.com\/en\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/","title":{"rendered":"Why it&#8217;s important for cells to make copies on an exacting schedule"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a39bad664947\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #dd3333;color:#dd3333\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #dd3333;color:#dd3333\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a39bad664947\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/buradabiliyorum.com\/en\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/#How_do_our_cells_stay_on_time_and_not_get_delayed_when_making_copies_of_themselves\" >How do our cells stay on time and not get delayed when making copies of themselves?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/buradabiliyorum.com\/en\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/#Are_cells_usually_on_a_tight_schedule_when_replicating_their_DNA\" >Are cells usually on a tight schedule when replicating their DNA?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/buradabiliyorum.com\/en\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/#Why_might_a_cell_become_delayed_or_stalled_when_replicating_its_DNA\" >Why might a cell become delayed or stalled when replicating its DNA?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/buradabiliyorum.com\/en\/why-its-important-for-cells-to-make-copies-on-an-exacting-schedule\/#Why_is_the_research_that_McClure_and_her_team_work_on_in_their_lab_so_important\" >Why is the research that McClure and her team work on in their lab so important?<\/a><\/li><\/ul><\/nav><\/div>\n<div>\n<div class=\"article-gallery lightGallery\">\n<div data-thumb=\"https:\/\/scx1.b-cdn.net\/csz\/news\/tmb\/2025\/mitosis.jpg\" data-src=\"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2025\/mitosis.jpg\" data-sub-html=\"Credit: Pixabay\/CC0 Public Domain\">\n<figure class=\"article-img\">\n            <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scx1.b-cdn.net\/csz\/news\/800a\/2025\/mitosis.jpg\" alt=\"mitosis\" title=\"Credit: Pixabay\/CC0 Public Domain\" width=\"800\" height=\"338\"\/><figcaption class=\"text-darken text-low-up text-truncate-js text-truncate mt-3\">\n                Credit: Pixabay\/CC0 Public Domain<br \/>\n            <\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<p>Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School of Medicine. She is focused on learning all about how cells replicate, or make copies of themselves. McClure and her research team seek to understand how cells copy all of their DNA on time and without genetic mistakes to pass down to next-generation cells.<\/p>\n<p>In this interview, she discusses how this works.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_do_our_cells_stay_on_time_and_not_get_delayed_when_making_copies_of_themselves\"><\/span>How do our cells stay on time and not get delayed when making copies of themselves?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Every cell in our bodies must make copies of themselves to keep us alive. Did you know that the genetic information within each cell that must be copied (your DNA) is the equivalent of a 200,000-page book?<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Are_cells_usually_on_a_tight_schedule_when_replicating_their_DNA\"><\/span>Are cells usually on a tight schedule when replicating their DNA?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>&#8220;As you might imagine, the process of cell replication is regulated and on a strict schedule, somewhat like writing an article for a <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/news\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"News\" target=\"_blank\" rel=\"noopener\">news<\/a>paper on a tight deadline,&#8221; she says.<\/p>\n<p>&#8220;You can think of the process of replication like a newspaper journalist interviewing multiple experts about an important new law and then reporting, or replicating, those facts in a news article. The journalist is expected to finish the article for publication in the newspaper by a certain deadline so that the public has accurate information about how the law will <a href=\"https:\/\/buradabiliyorum.com\/en\/category\/download-scripts-themes-apps\/\" data-internallinksmanager029f6b8e52c=\"9\" title=\"Download Scripts &amp; Themes &amp; Apps\" target=\"_blank\" rel=\"noopener\">app<\/a>ly to them on time before the law goes into effect. Likewise, a cell has a strict deadline to finish replicating all of its DNA before the cell divides.&#8221;<\/p>\n<p>McClure&#8217;s lab has been working on a surprising discovery\u2014sometimes things stall, and replication of the DNA does not finish on schedule! Her team has seen brand-new copies of DNA being made when the cell has already begun to divide, well after the typical deadline for copying DNA has passed. This delayed timing of replication has brought up a lot of questions that the lab is working hard to answer.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_might_a_cell_become_delayed_or_stalled_when_replicating_its_DNA\"><\/span>Why might a cell become delayed or stalled when replicating its DNA?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>&#8220;Thinking back to the journalist, missing the deadline may be due to simple procrastination or not finishing a task on time. But perhaps the delay is due to a problem with the audio equipment? Maybe the interview recording was distorted, and the journalist was stuck without precise quotes from their expert sources. Or, maybe their notes were pushed off the desk and scattered all out of order, requiring more time and help from co-workers to reorganize everything,&#8221; she continues.<\/p>\n<p>&#8220;No matter which issue came up, the deadline was missed, the reporter required additional help from others, and the article was submitted later than expected.&#8221;<\/p>\n<p>Despite the deadline-delaying issues that might pop up, it is also critical that the reporter files a factual story so that inaccurate information does not reach the public.<\/p>\n<p>In a similar way, McClure&#8217;s lab is investigating various cell factors that might help a stalled cell restart the replication process after the original replication deadline has passed.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_is_the_research_that_McClure_and_her_team_work_on_in_their_lab_so_important\"><\/span>Why is the research that McClure and her team work on in their lab so important?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Cancer cells spread in our bodies when cell replication makes a lot of errors and does not follow the usual schedule. This is why learning how a cell can overcome setbacks in replication is important\u2014one thing this research may help us do is figure out ways to prevent cancer from growing. By working to understand the ways that cells fix stalling during replication, McClure and her team hope to illuminate how cells become cancerous and, ultimately, advance treatments to stop the spread of cancer.<\/p>\n<div class=\"d-inline-block text-medium mt-4\">\n<p>\n\t\t\t\t\t\t\t\t\t\t\t\t\tProvided by<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCU Anschutz Medical Campus<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a rel=\"nofollow\" target=\"_blank\" class=\"icon_open\" href=\"http:\/\/www.ucdenver.edu\/anschutz\/\" target=\"_blank\" rel=\"nofollow\"><br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<svg>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<use href=\"https:\/\/phys.b-cdn.net\/tmpl\/v6\/img\/svg\/sprite.svg#icon_open\" x=\"0\" y=\"0\"\/>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/svg><br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/p>\n<\/p><\/div>\n<p>\t\t\t\t\t\t\t\t\t\t<!-- print only --><\/p>\n<div class=\"d-none d-print-block\">\n<p>\n\t\t\t\t\t\t\t\t\t\t\t\t<strong>Citation<\/strong>:<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\tQ&amp;A: Why it&#8217;s important for cells to make copies on an exacting schedule (2025, April 17)<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\tretrieved 17 April 2025<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\tfrom https:\/\/phys.org\/news\/2025-04-qa-important-cells-exacting.html\n\t\t\t\t\t\t\t\t\t\t\t <\/p>\n<p>\n\t\t\t\t\t\t\t\t\t\t\t This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no<br \/>\n\t\t\t\t\t\t\t\t\t\t\t part may be reproduced without the written permission. The content is provided for information purposes only.\n\t\t\t\t\t\t\t\t\t\t\t <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<p><script id=\"facebook-jssdk\" async=\"\" src=\"https:\/\/connect.facebook.net\/en_US\/sdk.js\"><\/script><\/p>\n<blockquote><p><strong><span style=\"color: #ff6600;\">If you liked the article, do not forget to share it with your friends. Follow us on\u00a0<span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/news.google.com\/publications\/CAAqBwgKMN63nwsw68G3Aw\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Google News<\/a><\/span>\u00a0too, click on the star and choose us from your favorites.<\/span><\/strong><\/p><\/blockquote>\n<blockquote>\n<p style=\"text-align: center;\"><strong>If you want to read more Like this articles, you can visit our <span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/en.buradabiliyorum.com\/category\/sciencee\/\" target=\"_blank\" >Science category.<\/a><\/span><\/strong><\/p>\n<\/blockquote>\n<p><span style=\"color: black;\"><a style=\"color: #ff9900;\" href=\"https:\/\/phys.org\/news\/2025-04-qa-important-cells-exacting.html\" target=\"_blank\" >Source<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Credit: Pixabay\/CC0 Public Domain Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School of Medicine. She is focused on learning all about how cells replicate, or make copies of themselves. McClure and her research team seek to understand how cells copy all of their DNA&#8230;<\/p>\n","protected":false},"author":1,"featured_media":663468,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/scx2.b-cdn.net\/gfx\/news\/hires\/2025\/mitosis.jpg","fifu_image_alt":"","footnotes":""},"categories":[16],"tags":[],"class_list":["post-663467","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciencee"],"_links":{"self":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/663467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/comments?post=663467"}],"version-history":[{"count":0,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/posts\/663467\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media\/663468"}],"wp:attachment":[{"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/media?parent=663467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/categories?post=663467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/buradabiliyorum.com\/en\/wp-json\/wp\/v2\/tags?post=663467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}