#A new way of combating fungal infections

“#A new way of combating fungal infections” Fighting fungal infection by natural means is what the microbiologist Florentine Marx-Ladurner and her team aim for. The researchers rely on the antifungal effect of fungi themselves. Credit: MUI/D/ Bullock In agriculture, fungicides are used to combat fungal infections, and in medicine, antimycotics—both of which have their drawbacks….

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#Editing immune response could make gene therapy more effective

“#Editing immune response could make gene therapy more effective” Samira Kiani, M.D, associate professor of pathology, member of the Pittsburgh Liver Research Center and the McGowan Institute for Regenerative Medicine. Credit: University of Pittsburgh Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of…

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#New method of biofortification that transforms leaves into nutrient stores

“#New method of biofortification that transforms leaves into nutrient stores” A tobacco plant with a virtual color that reflects its photosynthetic activity. Chloroplast-containing tissues appear in bluish-green color. The areas where chromoplast formation has been induced are seen in orange-red color. Credit: Luca Morelli. CRAG. A new collaborative study led by researchers from the Spanish…

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#Pollution linked to antibiotic resistance

“#Pollution linked to antibiotic resistance” Tim’s Branch, a stream with elevated nickel and uranium levels. Credit: Photo by David Scott Antibiotic resistance is an increasing health problem, but new research suggests it is not only caused by the overuse of antibiotics. It’s also caused by pollution. Using a process known as genomic analysis, University of…

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#Cold-sensitive staphylococci reveal a weakness

“#Cold-sensitive staphylococci reveal a weakness” Staphylococcus aureus (in yellow) magnified using an electron microscope. Credit: UNIGE Staphylococcus aureus—also known as “golden staph”—has the ability to develop in highly variable environmental conditions (on the skin, in the nose, on sterile surfaces, and so forth). Its great adaptability depends on an RNA helicase involved in the degradation…

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#Unparalleled inventory of the human gut ecosystem

“#Unparalleled inventory of the human gut ecosystem” Credit: CC0 Public Domain An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database, allowing researchers to explore the links between bacterial genes and proteins, and their effects on human health. This project was led by EMBL’s…

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#New bioink for cell bioprinting in 3-D

“#New bioink for cell bioprinting in 3-D” Bioprinting. Credit: Magnus Johansson A research group led by Daniel Aili, associate professor at Linköping University, has developed a bioink to print tissue-mimicking material in 3-D printers. The scientists have developed a method and a material that allow cells to survive and thrive. “Bioprinting is a new and…

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#The limitations of super-resolution microscopy overcome

“#The limitations of super-resolution microscopy overcome” (a) Three-dimensional Ex-dSTORM of 3.2 times expanded centrioles. Measuring bar one micrometer. (b) The enlarged section of (a) shows the nine-fold symmetry of the percentile. Measuring bar 500 nanometers. (c) Three-dimensional Ex-dSTORM of 3.1-fold expanded tubulin filaments. Measuring bar two microns. (d) The magnification in (c) shows a tubulin…

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#A histone modifier that facilitates an epigenetic switch

“#A histone modifier that facilitates an epigenetic switch” A depiction of the double helical structure of DNA. Its four coding units (A, T, C, G) are color-coded in pink, orange, purple and yellow. Credit: NHGRI Epigenetic regulation of gene expression is associated with switching between chromatin states characterized by distinct histone modifications. But how these…

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