#Influenza virus-induced oxidized DNA activates inflammasomes
“#Influenza virus-induced oxidized DNA activates inflammasomes” Credit: Pixabay/CC0 Public Domain Both influenza virus M2, a proton-selective ion channel essential for efficient viral replication, and PB1-F2 protein, which localizes to the mitochondria and attenuates host antiviral immunity, are involved in the inflammatory response by stimulating NLRP3 inflammasome-dependent IL-1β secretion. However, the precise mechanisms by which these…