#Researchers develop new cytosine base editors with high specificity and precision
“#Researchers develop new cytosine base editors with high specificity and precision” Top: Rationally-designed APOBEC3B deaminases. Middle: Evaluation of the specificity of CBEs by the orthogonal R-loop assay. Bottom: Evaluation of the specificity of CBEs by whole genome sequencing. Credit: IGDB Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without…