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“#Why do hospital germs bind more strongly to certain surfaces than to others?” Model of the adhesion mechanism by which the bacterium Staphylococcus aureus binds to hydrophobic (‘low-energy’) surfaces (left) compared with hydrophilic (‘high-energy’) surfaces (right). On the left, a large number of cell wall molecules (shown here as tiny compressible springs) are involved in…
“#Significant leap forward in method for cancer treatment” Credit: Pixabay/CC0 Public Domain Eindhoven University of Technology Professor Jan C.M. van Hest has announced a breakthrough in non-invasive cancer treatment. His Institute for Complex Molecular Systems partnered with several Chinese research institutions to test a nanotechnology that addresses the drawbacks to photodynamic therapy, an emerging cancer…
“#Sampling the gut microbiome with an ingestible pill” Credit: American Chemical Society Gut microbes affect human health, but there is still much to learn, in part because they’re not easy to collect. But researchers now report in ACS Nano that they have developed an ingestible capsule that in rat studies captured bacteria and other biological…
“#Engineered ‘nanobodies’ block SARS-CoV-2 from infecting human cells” Researchers designed a three-part molecule (pink) that nestles into the coronavirus spike protein (blue), pinning it into a conformation that makes it unable to stick to ACE2, the receptor through which the virus gains entry into human cells. Top view and side view shown. Credit: Walter and…
“#Real-time imaging shows how SARS-CoV-2 attacks human cells” QD608-RBD binds ACE2 and induces endocytosis. In this figure, the top panel shows ACE2-GFP (yellow) expressing cells binding and internalizing QD608-RBD (magenta). In the bottom panel, an inhibitor is added to prevent binding of QD608-RBD to ACE2-GFP, and the presence of ACE2-GFP on the cell surface is…
“#Researchers identify nanobody that may prevent COVID-19 infection” Credit: CC0 Public Domain Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells. The researchers believe this nanobody has the potential to be developed as an antiviral treatment against COVID-19….
“#Nano particles for healthy tissue” Phase contrast optical microscopy images of Nano Antioxidants samples after at normal gravity and weightlessness. Credit: European Space Agency “Eat your vitamins” might be replaced with “ingest your ceramic nano-particles” in the future as space research is giving more weight to the idea that nanoscopic particles could help protect cells…
“#Tiny biological package gets drug right to the ‘heart’ of transplant rejection” Johns Hopkins Medicine and NCI Frederick researchers have demonstrated in mice that they can easily deliver a promising anti-rejection therapy directly to a transplanted heart by packaging it within a tiny protein gel cocoon known as a hydrogel. The steps in constructing the…
“#Researchers develop dual-excitation decoding strategy for high-accuracy thermal sensing” Schematic illustration of the dual-excitation decoding strategy based on hybrid nanocomposites for thermal sensing by using the intensity ratio of two emissions at identical wavelength as the thermometric parameter. Credit: Prof. CHEN Xueyuan’s group Luminescent nanothermometry is a non-invasive method of detecting temperature in vivo, which…
“#Biocompatible TeSex nano-alloys for PT/PA/CT/PET imaging-guided NIR-II-photothermal therapy” Schematic illustration of TeSex alloying strategy and mechanisms for detoxification and theranostic multi-functionalization. Credit: Science China Press Nanotheranostics, integrating diagnostic and therapeutic functions by nanoplatform, exhibits a great potential in precision and personalized medicine, and also raises the requirement on multifunctional nanomaterials in pursuit of both good…