I know everything I am looking for is here, watch movies, watch series, education, games, exams, news, current events and many more.
“#Nanomaterials based strategies for treatment of hypoxic tumor” Schematic illustration of strategies for treatment of hypoxic tumor with nanomaterials. Credit: ©Science China Press Hypoxia is a typical characteristic of most tumors, owing to the fast consumption of oxygen by tumor tissue over the supply through malformed and abnormal tumor vasculature. Hypoxia in tumor tissue promotes…
“#A new platform for controlled delivery of key nanoscale drugs and more” These schematics and photographs illustrate a) a small capsule containing thousands of nano-sized droplets loaded with a drug or other active ingredient; and b) how the droplets burst from the capsule after a set amount of time. Credit: Liang-Hsun Chen In work that…
“#Giant nanomachine aids the immune system” Credit: CC0 Public Domain Cells that are infected by a virus or carry a carcinogenic mutation, for example, produce proteins foreign to the body. Antigenic peptides resulting from the degradation of these exogenous proteins inside the cell are loaded by the peptide-loading complex onto so-called major histocompatibility complex molecules…
“#Velcro method for more precise binding of drug particles” TU/e researchers prove selectivity based on number of receptors on the cell walls. Credit: TU Eindhoven In order to deliver drug particles to the right place in the body—a field known as nanomedicine—selectivity plays an important role. After all, the drug only has to attach itself…
“#Tiny engineered therapeutic delivery system safely solves genetic problems in mice” Credit: CC0 Public Domain Inserting genetic material into the body to treat diseases caused by gene mutations can work, scientists say—but getting those materials to the right place safely is tricky. Scientists report today in the journal Science Advances that the lipid-based nanoparticles they…
“#Toward a coronavirus breathalyzer test” Credit: CC0 Public Domain Few people who have undergone nasopharyngeal swabs for coronavirus testing would describe it as a pleasant experience. The procedure involves sticking a long swab up the nose to collect a sample from the back of the nose and throat, which is then analyzed for SARS-CoV-2 RNA…
“#New ‘nanopores’ technique offers proof-of-concept of earlier, safer tumor detection” Specific detection of Point-Mutation-Position using biological nanopore. Credit: Ryuji Kawano, TUAT In recent years, a non-invasive biopsy method called liquid biopsy has shown promise as a potential alternative to tissue biopsy, currently the gold standard in cancer detection and diagnosis. A tissue biopsy sample—traditionally collected…
“#Research exposes new vulnerability for SARS-CoV-2” Computer model showing poly basic cleavage sites on the novel coronavirus’ spike protein. Credit: Northwestern University. Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus’ infamous spike protein—illuminating a relatively simple, potential treatment pathway. The spike protein contains the virus’ binding site, which adheres to host…
“#Nanocatalysts that remotely control chemical reactions inside living cells” Credit: Pohang University of Science & Technology (POSTECH) The enzymes responsible for catalytic reactions in our body’s biological reactions are difficult to use for diagnosis or treatment as they react only to certain molecules or have low stability. Many researchers anticipate that if these issues are…
“#Epirubicin-loaded nanomedicines beat immune checkpoint blockade resistance in glioblastoma” Left: Hydrophobic epirubisin is conjugated to one end of hydrophilic polyethylene glycol (PEG) chain with aspartate-hydrazide as a linker. In water, this molecule is self-assembled to form nano-micelles (Epi/m). Upper right: PTEN( ) or PTEN(-) GBM was transplanted into the brain of mice, and Epi/m and…