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“#Bioactive natural compounds for the fight against cancer” Soy plants produce glyceollins in response to pathogen attack such as fungi, bacteria or UV irradiation, in order to maintain their health. Credit: pixabay.com Phytoalexins are bioactive phytochemicals that have attracted much attention in recent years due to their health-promoting effects in humans and their vital role…
“#Molecular simulations show how drugs block key receptors” Credit: CC0 Public Domain Many pharmaceuticals work by targeting what are known as ‘G-protein-coupled receptors.’ In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used in new immunotherapy against cancer bind to these receptors….
“#Transgenic rice lowers blood pressure of hypertensive rats” Credit: American Chemical Society In the future, taking your blood pressure medication could be as simple as eating a spoonful of rice. This “treatment” could also have fewer side effects than current blood pressure medicines. As a first step, researchers reporting in ACS’ Journal of Agricultural and…
“#’Unboil an egg’ machine creates improved bacteria detector” Credit: Pixabay/CC0 Public Domain Traditional fluorescent dyes to examine bacteria viability are toxic and suffer poor photostability—but using the VFD has enabled the preparation of a new generation of aggregation-induced emission dye (AIE) luminogens using graphene oxide (GO), thanks to collaborative research between Flinders University’s Institute for…
“#Click… Resistant bacteria caught in the act” As humanity fights against the coronavirus, the battle against antibiotic resistant bacteria continuesScientists at UCLouvain have succeeded in capturing unique images of protein soldiers that help bacteria resist drugs. This discovery is published in the prestigious scientific journal Nature Chemical BiologyThe image recordings will make it possible to…
“#Scientists produce first open source all-atom models of COVID-19 ‘spike’ protein” A model of an S-protein. Credit: Dr. Yeolkyo Choi/Lehigh The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The “spike” or S protein facilitates viral entry into host cells. Now a group of researchers from Seoul National University in…
“#History of insightful HIV research inspires neutron scattering approach to studying COVID-19” The three-dimensional structure of the SARS-CoV-2 main protease. The molecular dimer complex consists of a single monomer (green) bound to another monomer (pink) where a drug inhibitor would bind to a catalytic site cavity to prevent the virus from replicating. Credit: ORNL/Andrey Kovalevsky,…