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“#Rock-breathing bacteria are electron spin doctors, study shows” Electrons that shuttle through protein “wires” between bacterial cells and surfaces outside those cells tend to have a particular quantum spin. Credit: Katya Kadyshevskaya Electrons spin. It’s a fundamental part of their existence. Some spin “up” while others spin “down.” Scientists have known this for about a…
“#Using electricity to break down pollutants left over after wastewater treatment” Credit: CC0 Public Domain Pesticides, pharmaceutical products, and endocrine disruptors are emerging contaminants often found in treated domestic wastewater, even after secondary treatment. Professor Patrick Drogui of the Institut national de la recherche scientifique (INRS) and his team have tested the effectiveness of a…
“#How good gut bacteria help reduce the risk for heart disease” Credit: CC0 Public Domain Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: The potential to reduce the risk for heart disease. The bacteria’s activity in the intestines reduces production…
“#Helping drug-delivering particles squeeze through a syringe” Credit: CC0 Public Domain Microparticles offer a promising way to deliver multiple doses of a drug or vaccine at once, because they can be designed to release their payload at specific intervals. However, the particles, which are about the size of a grain of sand, can be difficult…
“#Researchers discover a novel mechanism regulating planar cell polarity” Transport vehicles carrying Frizzled-6. Credit: HKUST Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function. Defects in PCP are associated with a variety of human diseases including…
“#Toward improved wound healing: Chemical synthesis of a trefoil factor peptide” Studies demonstrated that trefoil factor peptides are locally produced to combat inflammation and injuries of the gastrointestinal tract by accelerating wound healing. Credit: Universität Wien The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of…
“#Sorting and secreting insulin by expiration date” Researchers took this image of an insulin-secreting cell from a mouse using a technique to label insulin granules, by age. In younger granules, the marker emits a green fluorescent light; as granules get older, the marker begins to emit a red fluorescence. The researchers found that cells’ preference…
“#How do bacteria build up natural products?” A complex of three proteins protects the highly reactive hexaketide when it is extended to the octaketide. In cooperation with other proteins, important natural substances are produced from the resulting octaketide. Credit: Maximilian Schmalhofer and Prof. Dr. Michael Groll/TUM The active agents of many drugs are natural products,…
“#Parasite research heats up” Intracellular Toxoplasma parasites expressing the genetically encoded calcium indicator GCaMP. Parasites were treated with A23187, a compound that causes influx of calcium and stimulates parasite egress. Credit: Whitehead Institute for Biomedical Research Apicomplexan parasites infect hundreds of millions of people around the world each year. Several species of apicomplexan parasites in…
“#New light-based method for faster ‘green’ production of building blocks for medicines” The Vapourtec flow device used for the experiments in this study. Credit: Timothy Noël, TU/e In industry, gaseous hydrocarbons such as ethane and methane are frequently changed into molecules that can act as building blocks for pharmaceuticals and agrochemicals. Typically, these processes take…