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“#Genetic detectives ID microbes suspected of slowly ruining humanity’s treasures” Photo summary of the various artworks sampled for the study “Characterizing microbial signatures on sculptures and paintings of similar provenance.” Circles indicate swabbed areas on each sample artwork. Credit: JCVI A new study of the microbial settlers on old paintings, sculptures, and other forms of…
“#Lead-Seq: A new high-throughput structure mapping method for RNA” Franz Narberhaus and Vivian Brandenburg are discussing one of the deciphered RNA structures. Credit: RUB, Marquard Researchers from Bochum and Münster have developed a new method to determine the structures of all RNA molecules in a bacterial cell at once. In the past, this had to…
“#Earth’s species have more in common than previously believed” Credit: CC0 Public Domain The Earth hosts an abundance of life forms—from well-known animals and plants to small, more hardy life forms such as archaea, viruses and bacteria. These life forms are fundamentally different all the way down to the cell level—or so scientists thought. Now,…
“#Mapping the genome could help in race to save native rat” Credit: CC0 Public Domain Scientists from The University of Western Australia have unveiled a genetic analysis of an endangered native rodent, which could help researchers and conservation authorities better understand how to protect the Australian species. DNA Zoo Australia Director Associate Professor Parwinder Kaur,…
“#New structural ‘map’ solves mysteries of gigantic gene regulator” Associate Professor James Murphy (L) and PhD student Ms Alexandra Gurzau (R) were part of a team who have extended the ‘map’ of the gigantic protein SMCHD1. Credit: Walter and Eliza Hall Institute, Australia Structural biology has been used to ‘map’ part of a protein called…
“#Accelerating biological systems design for sustainable biomanufacturing” iPROBE employs a mix-and-match analysis of different enzyme combinations to discover optimal biosynthetic pathways sustainable biomanufacturing. Credit: Northwestern University Northwestern University synthetic biologists have developed a new rapid-prototyping system to accelerate the design of biological systems, reducing the time to produce sustainable biomanufacturing products from months to weeks….
“#Team develops benchmark for detecting large genetic mutations linked to major diseases” The ‘book analogy’ is a popular way of explaining genome changes. If the human genome is considered a book, a new NIST-developed benchmark will help scientists better detect large chapters that are missing (deleted chapters) or not in the original (inserted chapters). Credit:…
“#Precision genome editing enters the modern era” Precision genome editors can correct single-letter DNA mutations, which underlie thousands of diseases. Scientists hope to one day use these editors therapeutically. Credit: Fairman Studios, LLC CRISPR has sparked a renaissance in genome editing. Now, next-generation CRISPR technologies let scientists modify the genome more efficiently and precisely than…
“#How young embryos conduct quality control” Apoptosis of aneuploid cells in mosaic epiblast during implantation. Credit: Zernicka-Goetz laboratory The first few days of embryonic development are a critical point for determining the failure or success of a pregnancy. Because relatively few cells make up the embryo during this period, the health of each cell is…
“#Team develops online atlas of human immunome for precision medicine” Credit: CC0 Public Domain Scientists from the SingHealth Duke-NUS Academic Medical Centre (AMC) have developed an interactive web-based atlas of the human immunome, or genes and proteins that make up the immune system. Known as EPIC (Extended Polydimensional Immunome Characterisation), the atlas hosts a comprehensive,…