#Studying many genes in many animals is key to understanding how humans can live longer

“#Studying many genes in many animals is key to understanding how humans can live longer” Credit: CC0 Public Domain Much of longevity and aging research focuses on studying extremely long-lived species, including bats, naked mole-rats and bowhead whales, to find genetic changes that contribute to long life. However, such work has yielded highly species-specific genetic…

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#Novel software reveals molecular barcodes that distinguish different cell types

“#Novel software reveals molecular barcodes that distinguish different cell types” Dotted box represents a tissue sample containing four cell types. Filled and empty circles represent methylated and unmethylated CpGs, respectively. Credit: Waterland lab/Genome Biology, 2020. There are about 75 different types of cells in the human brain. What makes them all different? Researchers at Baylor…

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#Scientists develop novel predictable multi-nucleotide deletion systems in plants

“#Scientists develop novel predictable multi-nucleotide deletion systems in plants” Figure: AIFD systems induce precise and predictable multi-nucleotide deletions in plants (a) Schematic representation of the AFID system. (b) Structures of AFIDs 1–3 and eAFID-3. (c) The proportions of predictable deletions generated by Cas9 and AFID-3. (d) Comparison of predictable deletion types between AFID-3 and eAFID-3….

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#Three new studies show unwanted changes in human embryo genome after CRISPR-Cas9 editing

“#Three new studies show unwanted changes in human embryo genome after CRISPR-Cas9 editing” CRISPR (= Clustered Regularly Interspaced Short Palindromic Repeats) DNA fragment, E.Coli. Credit: Mulepati, S., Bailey, S.; Astrojan/Wikipedia/ CC BY 3.0 Three teams working independently to test the possibility of using CRISPR–Cas9 gene editing to remove genetic defects in human embryos report finding…

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#Genome study opens pathway toward sustainable edible seaweed

“#Genome study opens pathway toward sustainable edible seaweed” The four strains were originally cultivated in different areas of Okinawa, labelled on the diagram. Credit: OIST Since the 1980s, in seaweed farms dotted along the coastline of the subtropical islands of Okinawa, farmers have cultivated the edible brown alga Okinawa mozuku (Cladosiphon okamuranus). Popular in Japanese…

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#Scientists create program that finds synteny blocks in different animals

“#Scientists create program that finds synteny blocks in different animals” Credit: Dmitry Lisovsky, ITMO.NEWS Modern genetics implies working with immense amounts of data which cannot be processed without the help of complex mathematical algorithms. For this reason, the task of developing special processing programs is no less important for bioinformatics specialists than that of genomic…

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#This enigmatic protein sculpts DNA to repair harmful damage

“#This enigmatic protein sculpts DNA to repair harmful damage” Structural models of a discontinuous DNA strand (left) and a discontinuous strand bent by a bound XPG catalytic core are overlaid on an electron micrograph of full-length XPG protein bound to a central bubble of discontinuous DNA. Credit: Jack Griffith/UNC Chapel Hill and Susan Tsutakawa/Berkeley Lab…

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#Researchers establish atlas of lipids in living organisms

“#Researchers establish atlas of lipids in living organisms” Credit: RIKEN In an effort intended to accelerate research into lipids, a research group led by scientists from the RIKEN Center for Integrative Medical Sciences (IMS), the RIKEN Center for Sustainable Resource Science (CSRS), and the Graduate School of Pharmaceutical Sciences, Keio University, have created a standardized…

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