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“#Revisiting energy flow in photosynthetic plant cells” Malate flow during C3 photosynthesis. Credit: The University of Hong Kong By developing innovative methods to visualize energy changes in subcellular compartments in live plants, the team of Dr. Boon Leong Lim, Associate Professor of the School of Biological Sciences of The University of Hong Kong, after showing…
“#Osmotic stress identified as stimulator of cellular waste disposal” Image of mouse astrocytes showing the actin cytoskeleton (red) and lysosomes (green) Credit: Tania Lopez-Hernandez Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids…
“#Researcher tackles long-standing mysteries about membrane protein structure” Nieng Yan’s research group poses for a group photo on the grounds of Princeton University, in the pre-social-distancing era. From left: Dr Hannah Leford, Dr. Yimo Han, Dr. Miaohui Hu, Dr. Xia Yao, Dr. Shuai Gao, Dr. Xuelan Wu, Prof. Nieng Yan, Dr. Xiao Fan, Dr. Hongwu…
“#Power outage: Research offers hint about heart weakness in Barth syndrome” Credit: CC0 Public Domain Barth syndrome is a rare condition that occurs almost exclusively in males. Symptoms include an enlarged and weakened heart. The condition is present at birth or becomes evident early in life. Life expectancy is shortened and there is no treatment….
“#Scientists propose a pseudotargeted metabolomics protocol” Pseudotargeted metabolomics method is a new method integrating the advantages of untargeted and targeted metabolomics methods. Credit: WANG Ting A research group led by Prof. Xu Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences proposed a protocol by systematically summarizing and upgrading the…
“#Scientists examine the impact of a very specific defect in DNA replication” In certain forms of replication stress, an active checkpoint actually allows cells to divide, causing worse damage than if it were missing entirely. (Illustration/iStock) USC researchers peering deep inside a living cell have discovered something surprising: Its system for preventing genetic damage linked…
“#The tug-of-war at the heart of cellular symmetry” By changing cell size, the team found two competing actomyosin networks: a ring-like centripetal actomyosin that pushes contents to the center, and radially-formed bridges that pull things to the edges. Credit: Kyoto University/Makito Miyazaki Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have…
“#Scientists identify the mechanism that regulates mitochondrial energy production” The figure represents the association of the respiratory complexes I, III and IV associated to form the N-respirasome super complex. The presence or absence of the SCAF1 protein determines the efficiency in the use of the energy source (food) to convert it into productive work by…
“#Scientists use protein, RNA to make hollow, spherical sacks called vesicles” A polarization microscopy image of protein-RNA vesicles created in the lab. The vesicles—hollow, spherical sacks—were made without traditional lipid building blocks. The microscopy image shows an optical birefringent pattern typical of liquid crystalline materials. Credit: Ibraheem Alshareedah Using protein and RNA, scientists have created…
“#Slow-growing rotavirus mutant reveals early steps of viral assembly” Rotaviruses infect cells to produce more viruses. One of the first steps of rotavirus replication is building rotavirus factories called viroplasms, seen in panel A as round, yellow dots inside rotavirus-infected monkey kidney epithelial cells (cell nuclei are colored in teal). But when rotaviruses carry the…