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“#RNA information transfer could be used in repairing DNA” This is a computer graphic of an RNA molecule. Credit: Richard Feldmann/Wikipedia Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When…
“#New study finds two amino acids are the Marie Kondo of molecular liquid phase separation” New research uncovers that the amino acids arginine (pink) and lysine (green) can form coexisting liquid phases with unique properties. Credit: Rachel Fisher The last several years have brought mounting evidence that the molecules inside our cells can self-organize into…
“#Structure of the enzyme behind the world’s smallest turbine, solved” Rows of ATP synthase as they would form on the ridges of mitochondrial membranes. ATP, ADP and lipids are shown in bright colours. Credit: Gergely Pinke / IST Austria The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP’s central role,…
“#Scientists study color change from green to red in the fluorescent protein” Model of the intermediate state of a chromophore and its interaction with proteins during anaerobic photoconversion of GFP. Credit: Frontiers in Molecular Biosciences Scientists from the Skolkovo Institute of Science and Technology (Skoltech), the Institute of Bioorganic Chemistry (IBCh RAS) and Lomonosov Moscow…
“#Finding a handle to bag the right proteins” The conjugated fluorophore is efficiently excited by widely available UV radiation sources. Credit: KAUST Purifying specific protein molecules from complex mixtures will become easier with a simpler way to detect a molecular tag commonly used as a handle to grab the proteins. Proteins, comprising many linked amino…
“#Viruses play critical role in evolution and survival of the species” This illustration shows the four stages of mouse spermatogenesis analyzed in research published Sept. 7, 2020, in Nature Structural & Molecular Biology. Credit: Cincinnati Children’s As the world scrambles to control the growing COVID-19 coronavirus pandemic, new research in Nature Structural & Molecular Biology…
“#Inheritance in plants can now be controlled specifically” An inversion (left) in thale cress (background) can be undone with CRISPR/Cas (center) to reactivate the exchange of genes (right) in the said section. Credit: Michelle Rönspies/KIT A new application of the CRISPR/Cas molecular scissors promises major progress in crop cultivation. At Karlsruhe Institute of Technology (KIT),…
“#Scientists discover new rules about ‘runaway’ transcription” Researchers discovered a new system of transcription and translation in bacteria, where the polymerase (pink) in B. subtilis “runs away” from the ribosome (blue). Credit: Grace Johnson On the evolutionary tree, humans diverged from yeast roughly 1 billion years ago. By comparison, two seemingly similar species of bacteria,…
“#Plant pathogens reorder physical structures of effectors to escape plant recognition” Phytophthora infestans is an oomycete, or water mold, that causes the devastating potato disease known as late blight or potato blight and was responsible for the famous Irish Famine of the 1840s. In a recently published study, a group of scientists focused on the…
“#Open access resource provides most comprehensive library for biological protein interactions” Researchers looking for up to date information about protein interactions within cells will benefit from a new open source resource created by academics at the University of Reading. PINOT, the Protein Interaction Network Online Tool, is an open access resource which provides researchers with…