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“#Lab finds new levels of detail about key membrane proteins” Structure of cell-to-cell communication channels (Connexin-46/50) resolved at 1.9 Å resolution by the Reichow Lab, using electron cryo-microscopy (CryoEM). This work provides a view of these communication channels (white), as well as ordered water molecules (red) and surrounding lipids (blue), with near-atomic level detail for…
“#Binding sites for protein-making machinery” Ribosomes are the cell’s protein-making machinery. They read the genetic information encoded in messenger RNA (violet) and translate it into proteins (yellow). Credit: Science Photo Library ETH Zurich researchers can predict how tightly a cell’s protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different…
“#CRISPaper: Understanding gene-editing through art” Credit: CC0 Public Domain To Sheng-Ying Pao, the power of reframing CRISPR lies in what is absolutely ordinary: paper. In CRISPaper, Pao revisited a cultural past in the ancient art of papermaking. Over thousands of years, farmers painstakingly converted the wild rice plant into a staple crop. Today, researchers are…
“#Researchers reveal molecular structures involved in plant respiration” Credit: CC0 Public Domain All plants and animals respire, releasing energy from food. At the cellular level, this process occurs in the mitochondria. But there are differences at the molecular level between how plants and animals extract energy from food sources. Discovering those differences could help revolutionize…
“#Accumulating extra genome copies may protect fly brain cells during aging” These images show glial cells of the optic chiasm in the adult fly brain that have accumulated extra genome copies. Both images show the same cells, but the second (right) is a higher-magnification image. The first (left) shows the glial cell marker, stained with…
“#Researchers develop new system to conduct accurate telomere profiling in less than 3 hours” A magnified image captured by the device used to perform STAR assay. Different fluorescent intensities reflect the length variations in individual telomere molecules. Credit: National University of Singapore The plastic tips attached to the ends of shoelaces keep them from fraying….
“#Super-resolution imaging breakthrough in living cells” Credit: PublicDomainPictures from Pixabay Edinburgh scientists have developed a new imaging technique that reveals the inner workings of living cells in stunning detail and could pave the way to a better understanding of many diseases. The new super-resolution imaging technique—LIVE-PAINT- provides a flexible and powerful way of tracking individual…
“#Size may not matter when estimating community energy use” Phytoplankton communities are made of different species which were used to understand how size and composition affect total metabolism. Credit: Dr Giulia Ghedini Ecologists often want to understand how a community functions. For example, how much food does a community of animals consume every day? Or…
“#Regulation of the MLH1-MLH3 endonuclease in meiosis” Credit: Nature Reconstitution of the activation of the MLH1–MLH3 endonuclease shows how crossovers are formed during meiosis. When DNA breaks, cells use the homologous recombination pathway to accurately repair the break, so that DNA is fixed and no mutations are introduced during the repair process. When multiple DNA…
“#Biomedical scientists piece together how medication paralyzes parasitic worms” Credit: CC0 Public Domain For years, many scientists and medical professionals likely misunderstood how a commonly prescribed medication for elephantiasis battled the disease, but a new study sets the record straight. The study, published in the peer-reviewed scientific journal Communications Biology, shows how the medication, diethylcarbamazine,…