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“#Start here to make a protein: Structure of mRNA initiation complex could give insight into cancer and other diseases” Researchers at the University of California, Davis and the MRC Laboratory of Molecular Biology in Cambridge, U.K. have solved the the structure of the complex formed when mRNA is being scanned to find the starting point…
“#New computational tool enables prediction of key functional sites in proteins based on structure” Credit: Unsplash/CC0 Public Domain A new technology that uses a protein’s structure to predict the inner wiring that controls the protein’s function and dynamics is now available for scientists to utilize. The tool, developed by researchers at Penn State, may be…
“#Novel technology for the selection of single photosynthetic cells” PhenoChip- a microfluidic device for the single cell phenotyping of unicellular phototrophs such as microalgae and cyanobacteria. Credit: Lars Behrendt You might need a microscope to witness the next agricultural revolution. New research, published in the journal Science Advances, demonstrates how microfluidic technologies can be used…
“#Engineers reprogram yeast cells to become microscopic drug factories” The stylized yeast cells depicted in several leaves and flower petals are an artist’s interpretation of how scientists, using the tools of synthetic biology, genetically engineered yeast to brew plant-based medicines that traditional societies discovered in nature. Credit: Jennifer Cook-Chrysos Since antiquity, cultures on nearly every…
“#Mapping the 3-D geometry of SARS-CoV-2’s genome” Colorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID The novel coronavirus uses structures within its RNA to infect cells. Scientists have…
“#Researchers develop a yeast-based platform to boost production of rare natural molecules” Credit: CC0 Public Domain Many modern medicines, including analgesics and opioids, are derived from rare molecules found in plants and bacteria. While they are effective against a host of ailments, a number of these molecules have proven to be difficult to produce in…
“#Barcoding long DNA quantifies CRISPR effects” The sequencing setup for the study: an Oxford Nanopore sequencer and a laptop computer. The screen in background shows the DNA strand fed through the sequencer. Credit: 2020 KAUST Mo Li. Current sequencing techniques lack the sensitivity to detect rare gene mutations in a pool of cells, which is particularly…
“#We can programme plants to grow biomolecules. Is farming the future of vaccines?” Special biomolecules and compounds for medical use are being grown in plants like the commercial tobacco plant. Credit: Pixabay/Couleur, licenced under Pixabay licence On the southern outskirts of the city of Owensboro in Kentucky, US, there is a square, nondescript building. Inside,…
“#Researchers create bioluminescent tag to detect DNA break repair” Credit: CC0 Public Domain A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. The international team’s novel bioluminescent repair reporter (BLRR)-based system can be used…
“#Tiny endangered shrimp may get big hand from environmental DNA testing” The San Diego fairy shrimp lives in vernal pools, puddles that appear after rains and dry up within a couple months. Credit: Wikimedia Commons The San Diego fairy shrimp, a miniscule, puddle-dwelling crustacean that provides food for migrating birds, is nearing extinction as humans…