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“#Team discovers a new role for a well-known molecule as a plant hormone” ACC facilitates fertilization. The pollen tubes (stained in blue) fertilize only some of the ovules when there is less ACC. Successful fertilization is seen as blue dots inside the white ovules. Credit: Dr. Wangshu Mou Researchers at the University of Maryland (UMD)…
“#Landmark paper calls for need to develop the world’s microbiome biobanking infrastructure” Part of the culture collection at CABI’s laboratories in Egham, UK. Credit: Tom Swindley/CABI A team of scientists led by CABI’s Dr. Matthew Ryan has outlined a series of challenges and opportunities presented in a necessary review of how microbiomes—biological communities including bacteria,…
“#Recipe for success: Interaction proteomics become a household item” The MAC-tag workflow allows molecular microscopy of proteins. Credit: Ella Maru Studio Proteins in human cells do not function in isolation and their interactions with other proteins define their cellular functions. Therefore, detailed understanding of protein-protein interactions (PPIs) is the key for deciphering regulation of cellular…
“#New research reveals previously hidden features of plant genomes” P2IRC researcher Andrew Sharpe with the PromethION high throughput DNA and RNA sequencing device at GIFS. Credit: David Stobbe An international team led by the Plant Phenotyping and Imaging Research Centre (P2IRC) at the University of Saskatchewan (USask) and researchers at Agriculture and Agri-Food Canada (AAFC)…
“#De novo synthesis of a wide range of nucleoside analogs using simple achiral starting materials” Nucleoside analogs: objectives and obstacles. WHO, World Health Organization; e.r., enantiomeric ratio. Credit: Science 07 Aug 2020: Vol. 369, Issue 6504, pp. 725-730 DOI: 10.1126/science.abb3231 A team of researchers from Simon Fraser University and Merck & Co. has developed a…
“#Creative block of molecular evolution: Adaptive mutations repeat themselves in tiny crustaceans of Lake Baikal” Credit: Pavel Odinev / Skoltech A group of scientists from Skoltech and the Institute for Information Transmission Problems of RAS (IITP RAS) showed, using Lake Baikal amphipods as an example, that parallel evolution driven by adaptations can be detected at…
“#Integration of gene regulatory networks in understanding animal behavior” Neuronal network (NN)–gene regulatory network (GRN) interactions. Spatial dimensions (Bottom): Different cells (neurons), connected by the NN, may exhibit different GRN activities, even though the GRN itself is unchanged. GRN includes activating (green arrow) and repressive (red hammer) relationships between genes (circles). Gene expression is indicated…
“#Scientists use CRISPR to knock down gene messages early in development” The development of mRNA knock-down technologies for use in vertebrate organisms such as zebrafish has been limited. CRISPR-RfxCas13d has been identified as an effective method for the systematic study of gene function in vivo during embryogenesis across a range of animal species. Credit: Bazzini…
“#Algorithm created by deep learning finds potential therapeutic targets throughout genome” Credit: CC0 Public Domain A team of researchers from New Jersey Institute of Technology (NJIT) and Children’s Hospital of Philadelphia (CHOP) have developed an algorithm through machine learning that helps predict sites of DNA methylation—a process that can change the activity of DNA without…
“#Comprehensive catalogue of the molecular elements that regulate genes” An artistic representation of gene regulating elements, which allow cells with the same genetic code to differentiate into many different tissues and play many varied roles in the body. Credit: Ella Maru Studio A 17-year research project has generated a detailed atlas of the genome that…