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“#Hidden in our genes: Discovering the fate of cell development” Mapping correlation between genes within a mouse olfactory bulb. Credit: Springer Nature/University of Sydney As cells develop, changes in how our genes interact determines their fate. Differences in these genetic interactions can make our cells robust to infection from viruses or make it possible for…
“#Meet baker’s yeast, the budding, single-celled fungus that fluffs your bread” Baker’s yeast, Saccharomyces cerevisiae, proofing with sugar and water in a 40-minute time-lapse animation. Credit: Douglas Levere / University at Buffalo They live in bread dough. They die in your oven. At the grocery store, where you buy them, they sit in little glass…
“#Scientists discover extraordinary regeneration of neurons” Color-processed microscopic image of a pair of Mauther cells (green) in a zebrafish. On the left is the head of the fish, on the right the tail. The two green areas on the left are the cell bodies of the Mauther cells, the structures running to the right are…
“#Vulnerability for at-risk populations identified in US influenza data” This digitally-colorized transmission electron microscopic image depicts the ultrastructural details of an influenza virus particle. Credit: CDC, Frederick Murphy A next-generation system for monitoring influenza outbreaks performs well overall, but reveals a critical lack of sufficient data to accurately monitor influenza in the most at-risk communities….
“#X-ray scattering shines light on protein folding” Figure. The scientists found that non-functional unfolded forms of the protein cytochrome c follow different pathways and timelines to reach a stable functional folded state. Credit: The Korea Advanced Institute of Science and Technology (KAIST) KAIST researchers have used an X-ray method to track how proteins fold, which…
“#Doing more with less: Sperm without a fully active tail move faster and more efficiently, new study finds” Credit: CC0 Public Domain Sperm cells moving their long tail to swim through the body in search of an egg is a familiar image, but a fully ‘powered’ tail may not be the key to success, according…
“#New insights revealed in the evolution of community-level heredity” Communities founded with an equal ratio of red-to-blue cells are assessed after a round of cell growth. Communities far from the optimal pink colour (1:1 ratio) are eliminated, whereas those close to the optimum are selected to leave offspring communities. Stochastic effects dominate early-stage evolution with…
“#Structural insights into Fe-S protein biogenesis” Crystal structure of the CIA targeting complex provides insights into Fe-S protein biogenesis. Credit: Friedrich Miescher Institute for Biomedical Research The cytosolic iron sulfur assembly (CIA) pathway is required for the insertion of Fe-S clusters into proteins, including many DNA replication and repair factors. Despite its essential cellular function,…
“#Histone H3-H4 tetramer found to be a copper reductase enzyme” Recombinant X. laevis histone H3-H4 tetramer interacts with cupric ions. (A) Left: X. laevis (Xl) nucleosome core particle structure [Protein Data Bank (PDB) 1KX5] (38). The box delineates the H3-H3′ interface. Right: Interface residues H3H113 and H3C110 are shown. (B) Alignment of the C-terminal region…
“#Researchers visualize new states of ribosome translation with cryo-EM” Credit: Pixabay/CC0 Public Domain The stages in which ribosomes synthesize life-sustaining proteins have been revealed in unprecedented real-time detail by UMass Medical School structural biologists Andrei Korostelev, Ph.D., and Anna Loveland, Ph.D. Their new study of this fundamental molecular mechanism, captured using state-of-the-art, time-resolved, cryo-electron microscopy…