#’Bystander’ cytosines meet their match in gene-editing technique

“#’Bystander’ cytosines meet their match in gene-editing technique” When consecutive cytosines are positioned in the editing window, the new A3G base editor developed at Rice University precisely modifies the single targeted C while minimizing unwanted C editing. Credit: Gao Lab/Rice University Biomolecular engineers at Rice University have found a C-worthy technique that dramatically enhances the…

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#Scientists uncover key process in the manufacture of ribosomes and proteins

“#Scientists uncover key process in the manufacture of ribosomes and proteins” Negin Khosraviani, Karim Mekhail and Karan (Josh) Abraham. Credit: University of Toronto Researchers at the University of Toronto have shown that an enzyme called RNA polymerase (Pol) II drives generation of the building blocks of ribosomes, the molecular machines that manufacture all proteins in…

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#Finding the missing step of an important molecular process

“#Finding the missing step of an important molecular process” This figure shows how bacterial and plant lysine catabolic pathways converge, while the highlighted box shows the enzymatic mechanism of the enzyme the researchers discovered and characterized. Credit: US Department of Energy Lysine is an important amino acid that must be supplied in our diets, as…

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#Power of DNA to store information gets an upgrade

“#Power of DNA to store information gets an upgrade” Credit: CC0 Public Domain A team of interdisciplinary researchers has discovered a new technique to store in DNA information—in this case “The Wizard of Oz,” translated into Esperanto—with unprecedented accuracy and efficiency. The technique harnesses the information-storage capacity of intertwined strands of DNA to encode and…

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#The colorful history of plastids

“#The colorful history of plastids” Schematic evolutionary tree of eukaryotes with an emphasis on photosynthetic lineages. Members of the Archaeplastida have primary plastids stemming directly from cyanobacteria. The primary plastids of red and green algae have spread from the Archaeplastida to other branches of the tree, including Rhizaria, Discoba, and Stramenopila. The colored taxon names…

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