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“#An open-source data platform for researchers studying archaea” Biologists found that the archaea Haloferax volcanii grows in a honeycomb-like fashion under specialized conditions. They hope to gain more insights into the microbes through a new initiative, the Archaeal Proteome Project. Credit: Laboratory of Mecky Pohlschroder Bioinformatics and big data analyses can reap great rewards for…
“#Label-free imaging helps predict reproductive outcomes” Phase imaging with computational specificity applies artificial intelligence to label-free spatial light interference microscopy data to map subcellular compartments, as illustrated. Credit: Beckman Institute for Advanced Science and Technology Researchers at the Beckman Institute for Advanced Science and Technology and the Department of Animal Sciences have collaborated to develop…
“#Advanced Cryo-EM reveals viral RNA replication complex structure in stunning detail” Cryo-EM imaging reveals high-resolution side and top views of the viral RNA replication “crown” complex structure. Credit: Paul Ahlquist, Morgridge Institute for Research For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral…
“#Decoding the language of cellular messaging” Cross-sections of a fruit fly embryo that has been stained with antibodies that recognize the FGF Pyramus (red), its receptor Heartless (green), and a marker of cell membranes (blue). Credit: Jingjing Sun Before the days of rote texting and email, if you wanted to communicate with a friend you…
“#Scientists find faster way to count animal sperm using DNA” Credit: CC0 Public Domain Researchers at the University of New Hampshire have identified a quicker and less expensive way to count sperm in lobsters that could help scientists looking at any animal better understand mating, a key aspect of species survival. “Scientists used to have…
“#Sperm discovery reveals clue to genetic ‘immortality’” Machinery of the jumping gene LINE1 (red) mounting an attack on the DNA (blue) of germ cells Credit: Professor Dónal O’Carroll New insights into an elusive process that protects developing sperm cells from damage in growing embryos, sheds light on how genetic information passes down, uninterrupted, through generations….
“#Megaphages harbor mini-Cas proteins ideal for gene editing” A megaphage (left), a member of a bacteriophage family Biggiephage, injects its DNA — including genes for CasΦ (red) — into bacterial cells to turn the bacteria against the phage’s competitor (top). The reddish Pac-Man-like figures are CasΦ proteins, enzymes that cut up viral DNA. The genome…
“#Researchers discover 2 paths of aging and new insights on promoting healthspan” UC San Diego biologists and bioengineers identified a master aging circuit that opens the door to genetically engineered prolonged life. Credit: Erik Jepsen/UC San Diego Publications Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the…
“#Synthetic mRNAs modified with sulfur atoms boost efficient protein synthesis” Phosphorothioate modification of mRNA increases the rate of translation initiation and the molecular designs for a high translation efficiency were optimized. This result provides a useful molecular design guideline for improving the translation quantity by chemical modification of mRNA. Credit: Nagoya University Since mRNAs play…
“#Blood iron levels could be key to slowing ageing, gene study shows” Credit: CC0 Public Domain Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists. The international study using genetic data from more than a million people suggests that maintaining healthy levels…