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“#How cells keep growing even when under attack” Biochemist Peter Chien, reports on recent experiments and discovery about how bacteria switch gears to respond to different stresses but still maintain normal cell functions like DNA replication, in Molecular Cell. Credit: UMass Amherst In an unexpected new finding, biochemists at the University of Massachusetts Amherst report…
“#Acetate regulates immune cells for a precisely orchestrated immune defense” Credit: CC0 Public Domain The concentration of acetate increases particularly sharply at the site of an infection in the body. As reported in the journal Cell Metabolism by a team of researchers from the University of Basel and colleagues, acetate supports the function of certain…
“#Scientists find how clock gene wakes up green algae” ROC75 plays a crucial role in the night-to-day transition of the circadian rhythm in C. reinhardtii. Credit: Takuya Matsuo A team of researchers from Nagoya University, Japan, has found the mechanism of the night-to-day transition of the circadian rhythm in green algae. The findings, published in the…
“#Study sheds new light on cell migration” Credit: CC0 Public Domain The 3-D structure of the ELMO / DOCK2 complex, an important molecular machine that plays a crucial role in cell migration in the body, is now better understood thanks to new research by scientists in Montreal and the United Kingdom. Working with David Barford of…
“#Cells under stress get into molecular ‘traffic jams,’ triggering a suicide pathway” A model of a human ribosome. Credit: National Institutes of Health 3D Print Exchange When cells experience a high level of stress—for example, when they are exposed to too much UV light—ribosomes inside the cell collide and get into traffic jams. Now, Johns…
“#AI may offer a better way to ID drug-resistant superbugs” A new method for identifying strains of bacteria and guessing their resistance to antibiotics uses an AI model to analyze their growth dynamics in culture. Credit: Duke University Biomedical engineers at Duke University have shown that different strains of the same bacterial pathogen can be…
“#Mitochondrial metabolite mediates longevity through epigenomes” Model of acetyl-CoA links mitochondrial stress to longevity via NuRD-mediated chromatin remodeling. Credit: IGDB In a study published in Science Advances, researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences revealed that mitochondrial metabolite acetyl-CoA links mitochondrial stress to the nuclear epigenome via…
“#How human sperm really swim: New research challenges centuries-old assumption” The sperm tail moves very rapidly in 3D, not from side-to-side in 2D as it was believed. Credit: polymaths-lab.com A breakthrough in fertility science by researchers from Bristol and Mexico has shattered the universally accepted view of how sperm ‘swim’. More than three hundred years…
“#Detective work in the cell: Scientists uncover a new RNA-modifying enzyme” Credit: CC0 Public Domain Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have identified a unique chemical reaction at the end of RNA molecules for the first time…
“#Stay or leave? A tale of two virus strategies revealed by math” Using a model to fit experimental data measured for cells infected with two strains of hepatitis C in the lab, researchers have quantified the viruses’ preferences to adopt either a stay or leave strategy. The stay strategy emphasizes keeping copies of genetic code…